What is Haldol (haloperidol)?
Haldol (haloperidol) is an antipsychotic medication.
It also is used to control tics and vocal utterances that are part of
Is Haldol (haloperidol) available as a generic drug?
Do I need a prescription for Haldol (haloperidol)?
Why is Haldol (haloperidol) prescribed to patients?
Schizophrenia is the most disabling mental illness.
What are the side effects of Haldol (haloperidol)?
The most common side effects associated with Haldol are:
- extrapyramidal effects (sudden, often jerky, involuntary motions of the head, neck, arms, body, or eyes,
muscle stiffness, akathisia, Parkinsonism),
- tiredness, and
Other important side effects are:
- weight gain,
- erectile dysfunction,
- menstrual irregularities,
- dry mouth,
- vomiting, and
Haldol may cause a condition called "orthostatic hypotension"
during the early phase of treatment (first week or two). Orthostatic hypotension
causes patients to become dizzy upon arising from a lying or sitting position
because of a drop in blood pressure.
What is the dosage for Haldol (haloperidol)?
- The recommended oral dose for schizophrenia is 0.5-5 mg two or
three times daily up to a maximum dose of 30 mg daily. The lactate solution dose
is 2-5 mg every 4-8 hours as needed by intramuscular injection. The lactate
solution may also be administered by intravenous injection at 1-2 mg every 2-4
hours and titrated to effect. The maximum single injection dose is 50 mg and the
maximum daily dose is 500 mg daily. The dose for the decanoate solution is 10-20
times the daily oral dose once monthly by intramuscular injection. The decanoate
solution should not be administered intravenously.
- The recommended dose for
treating Tourette’s syndrome is 0.5-5 mg orally two or three times daily.
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Which drugs or supplements interact with Haldol (haloperidol)?
The narcotic class of pain medications and its
derivatives for example:
- oxycodone and
- propoxyphene (Darvon)
tricyclic class of antidepressants
Some antihistamines for example:
antihypertensive medications for example:
may increase the elimination of Haldol, rendering the Haldol less
effective. Rifampin (Rifadin) may decrease the elimination of
increasing the risk of side effects from Haldol.
Is Haldol (haloperidol) safe to use during pregnancy or while breastfeeding?
- Neonates exposed to antipsychotics during the 3rd trimester
of pregnancy may develop withdrawal symptoms and extrapyramidal symptoms.
- Haldol is secreted into
breast milk. It should not be used while breast feeding.
What else should I know about Haldol (haloperidol)?
What preparations of Haldol (haloperidol) are available?
- Tablets: 0.5, 1, 2, 5, 10, and 20 mg.
- Oral Concentrate:
1 and 2 mg/ml.
- Injectable solution (lactate): 5 mg/ml;
- Injectable solution (decanoate):
50 and 100 mg/ml.
How should I keep Haldol (haloperidol) stored?
- Tablets should be stored at room temperature, 15-30 C (59-86
How does Haldol (haloperidol) work?
- Haloperidol interferes with the effects of neurotransmitters in the
brain which are the chemical messengers that nerves manufacture and release to
communicate with one another. Haloperidol blocks receptors for the
neurotransmitters (specifically the
dopamine and serotonin type 2 receptors) on
the nerves. As a result, the nerves are not "activated" by the neurotransmitters
released by other nerves.
When was Haldol (haloperidol) approved by the FDA?
- Haloperidol was approved by the FDA in 1967.