Diamox Brand (acetazolamide) Side Effects, Dosage & Uses

What is Diamox, Diamox Sequels (acetazolamide)?

Acetazolamide is a strong carbonic anhydrase inhibitor.

Why is Diamox, Diamox Sequels (acetazolamide) prescribed to patients?

Acetazolamide a prescription medicine used for the following

What brand names are available for acetazolamide?

Diamox and Diamox Sequels are the brand names available for acetazolamide in the US.

Do I need a prescription for Diamox, Diamox Sequels (acetazolamide)?


Is Diamox, Diamox Sequels (acetazolamide) available as a generic drug?


What are the side effects of Diamox, Diamox Sequels (acetazolamide)?

Common side effects include:

Other less common side effects include:

Possible serious side effects of Diamox:

Possible serious side effects include:

What is the dosage for Diamox, Diamox Sequels (acetazolamide)?

For the treatment of glaucoma: acetazolamide should be used as an adjunct to
the usual therapy.

  • The usual recommended dose for the treatment of
    open-angle glaucoma ranges
    from 250 mg to 1 gram of acetazolamide per day. Treatment with doses >1gram did
    not offer any additional benefits.
  • The usual recommended dose for the treatment of secondary glaucoma and for
    the preoperative treatment of some cases of closed-angle glaucoma is 250 mg
    every 4 hours. In more urgent cases, an initial dose of 500 mg followed by 125
    mg or 250 mg every 4 hours as be used.

For the treatment of seizures:

  • The manufacturer’s suggested total daily dose
    is 8-30 mg per kg in divided doses.
  • The optimum range appears to be from 375 to
    1000 mg, however, some patients may respond to lower doses.
  • When used with other
    anti-seizure medication, the starting dose of acetazolamide should be 250 mg,
    and it should then gradually be increased as necessary.

For congestive heart failure:

  • To remove excess fluid in patients (diuresis) with

    congestive heart failure, the starting dose is usually 250 to 375 mg
    administered once a day in the morning.

  • As tolerance may develop with use,
    this medication should be skipped for a day to allow the kidneys to recover in
    patients who stop responding to treatment. For best diuresis, acetazolamide
    should be given on alternate days, or for two days followed by one day off and
    then repeat.

For the treatment of excess water retention caused by medication:

  • The usual
    recommended dose is 250 to 375 mg once a day for one or two days, alternating
    with a day of rest.

For acute mountain sickness:

  • The usual recommended dose is 500 mg to 1000 mg per
    day in divided doses.
  • 1000 mg is recommended in cases of rapid ascent.
  • Preferably, treatment should be started 24-48 hours before ascent and continued
    for 48 hours while at high altitude, or longer as necessary to control symptoms.

Latest Heart News

Trending on MedicineNet

Which drugs or supplements interact with Diamox, Diamox Sequels (acetazolamide)?

  • Acetazolamide should not be used with other carbonic anhydrase inhibitors
    such as
    methazolamide (Neptazane). Use of two carbonic anhydrase inhibitors may
    cause dangerously low levels of blood potassium

Is Diamox, Diamox Sequels (acetazolamide) safe to use during pregnancy or while breastfeeding?

  • There are no adequate studies evaluating the use of acetazolamide
    during pregnancy. Evidence of
    birth defects was observed with administration of oral
    and injectable acetazolamide in mice, rats, hamsters, and rabbits. Therefore,
    acetazolamide should only be used during pregnancy if the potential benefit of
    treatment outweighs the potential risk to the unborn baby. Acetazolamide is
    classified as FDA pregnancy risk category C.
  • It is not known whether acetazolamide is excreted into human milk. Because
    many drugs are excreted into human milk and can cause side effects in the
    nursing infant, the manufacturer recommends that patients should discontinue
    nursing or discontinue acetazolamide, taking into account the importance of
    treatment to the mother. However, according to the American Academy of Pediatrics, acetazolamide is usually considered to be compatible with


What causes dry eyes?
See Answer

What else should I know about Diamox, Diamox Sequels (acetazolamide)?

What preparations of Diamox, Diamox Sequels (acetazolamide) are available?
  • Oral tablets: 125 and 250 mg
  • Oral capsules extended release (12hr): 500 mg
  • Powder for injection: 500 mg
How should I keep Diamox, Diamox Sequels (acetazolamide) stored?
  • All oral preparations of acetazolamide should be stored at room temperature.
  • Before mixing, injection acetazolamide should be stored at room temperature,
    between 20 C and 25 C (68 F and 77) F.
  • After mixing, acetazolamide injection should be stored in the refrigerator,
    between 2.2 C and 7.7 C (36 F and 46 F) and used within 12 hours of mixing.
How does Diamox, Diamox Sequels (acetazolamide) work?
  • Carbonic anhydrase
    is an enzyme found within the
    red blood cells and helps to regulate the acidity
    and fluid balance in various organs throughout the body. Carbonic anhydrase
    catalyzes a reversible reaction that converts carbon dioxide and water into
    carbonic acid, which can then breakdown into protons and bicarbonate ions.
  • In the kidneys and the eyes, carbonic anhydrase promotes the reaction that
    produces bicarbonate ions and acid to regulate the amount of fluid within these
    organs. When the delicate balance of this reaction is disturbed, medical
    problems such as glaucoma and excess fluid retention (edema) may occur.
    Beneficial effects observed in the treatment of glaucoma include decreases in
    the secretion of aqueous humor in the eye and intraocular pressure.
  • When used as
    a diuretic (water-pill) in patients who have abnormal fluid retention (for
    example, heart failure), acetazolamide works in the kidney to promote a
    reversible reaction that results in the loss of bicarbonate, which carries with
    it sodium, water, and potassium. In-addition to causing diuresis (water loss),
    the urine becomes more alkaline or basic (pH increases). Alkalization of the
    urine causes an increase in the reabsorption of ammonia by the renal tubules.
  • Acetazolamide is also used to treat and prevent symptoms of acute mountain
    sickness (AMS) such as
    shortness of breath,
    drowsiness, and
    fatigue. Compared to placebo, 250 mg acetazolamide every 8-12
    hours or 500 mg controlled-release capsule once daily was effective in
    preventing symptoms of acute mountain sickness before and during rapid ascent to altitude. Compared
    to placebo, acetazolamide treated patients experienced fewer and/or less severe
    symptoms, had better lung function, and experienced less difficulty in sleeping.
  • Acetazolamide is also used with other medications to treat certain forms of

Check Also

강남 셔츠룸 서울부장

강남 셔츠룸 매정한 나라에요 ㅋㅋㅋ 신규오픈 매장으로 설치 물품들이 많습니다. 역시 시부야 아니랄까봐 우리 나라 정서가 두 들겨야 흥이 더 나는듯 합니다. 아직 소버일때 우리 여자 예쁘니 직원들이랑 사진찍고 놀기  5~2배 정도 들었던것같아요 일환이었던 월성 원전 1호기 조기폐쇄에 대한 감사는 수위 조절이 실패해서 포기 햇엇드랫죠;; 대량 매출 가능한 입지라 확신합니다. 게임센터 규모도 장난 아니더라구요 차량…

Leave a Reply