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pramoxine (Itch-X and others) – Topical: Side Effects, Dosage, and Interactions

What is pramoxine, and how does it work (mechanism of action)? Pramoxine is a topical (used on the skin) anesthetic (numbing agent). Topical anesthetics are chemicals that interfere with the function of the nerves that sense pain. Pramoxine may be used in persons who are allergic to other local anesthetics such as lidocaine, procaine, or …

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dalfampridine, Ampyra: Drug Facts, Side Effects and Dosing

What is dalfampridine, Ampyra, and how does it work (mechanism of action)? Ampyra is an oral medication used for treating multiple sclerosis (MS). Its exact mechanism of action is unknown, but it is known to block movement of potassium between nerve cells. In animal studies Ampyra increased the conduction of nerve signals. The FDA approved Ampyra in December 1987. What …

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perphenazine and amitriptyline (Etrafon): Drug Side Effects

What is amitriptyline w/ perphenazine-oral, and how does it work (mechanism of action)? Perphenazine/amitriptyline is a combination of an antipsychotic and an antidepressant. Perphenazine is an antipsychotic that works in the brain and nervous system. Its exact mechanism of action is unknown. Amitriptyline is a tricyclic antidepressant. It is believed that in some patients with depression, abnormal levels of neurotransmitters …

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salsalate, Disalcid: Drug Facts, Side Effects and Dosing

What is salsalate, and how does it work (mechanism of action)? Salsalate is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating fever, pain, and inflammation in the body. Salsalate is converted in the body to salicylic acid which is its active form and is closely related to aspirin. Other NSAIDs include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen …

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cosyntropin (Cortrosyn): Facts About Drug Side Effects

What is cosyntropin-injectable, and how does it work (mechanism of action)? Cosyntropin is a manufactured version of the body's natural adrenocorticotropin hormone (ACTH). ACTH is produced by the pituitary gland in the brain. It stimulates the adrenal gland to release steroids including hydrocortisone and cortisone, androgens, as well as aldosterone. Cosyntropin has the same activity as ACTH. The FDA approved …

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choline magnesium salicylate, Trilisate: Drug Facts, Side Effects and Dosing

What is choline magnesium salicylate, and how does it work (mechanism of action)? Choline magnesium salicylate (or trisalicylate) is a type of nonsteroidal anti-inflammatory drug (NSAID), referred to as a salicylate, which is effective in treating fever, pain, and inflammation in the body. Other drugs within the same class are aspirin, diflunisal (Dolobid) and salsalate (Disalcid). They work by reducing …

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Conjugated Estrogens (Cenestin, Enjuvia, Estrace, and Others)

What are conjugated estrogens? Conjugated estrogens are mixtures of man-made or natural estrogens used as an external source and replacement for the natural female hormone. Estrogens have widespread effects on many tissues in the body. Estrogens cause growth and development of the female sexual organs and maintain female sexual characteristics such as the growth of underarm and pubic hair, body …

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bromfenac (Duract): Drug Facts, Side Effects and Dosing

What brand names are available for bromfenac? Duract

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boceprevir (Victrelis) Hepatitis C Drug Side Effects

What is boceprevir, and how does it work (mechanism of action)? Boceprevir is a man-made antiviral medication that targets hepatitis C virus (HCV). Similar drugs include simeprevir (Olysio) and telaprevir (Incivek). These drugs are called direct-acting antiviral agents because they act directly on hepatitis C virus. They block the replication of hepatitis C virus in human cells by binding to …

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blue-green algae (Cyanobacteria, Spirulina) Side Effects

What is blue green algae (Spirulina sp.)-oral, and how does it work (mechanism of action)? Blue-green algae is a natural herbal supplement. Blue-green algae has high amounts of protein, iron, and other minerals and claims have been made that it has beneficial effects on the immune system, inflammation, and against viral infections. Individuals should check with their physicians before using …

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