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Diflucan (fluconazole) Side Effects (Alcohol), Dosage & Pregnancy

What is Diflucan (fluconazole)? How does it work (mechanism of action)?

Diflucan (fluconazole) is an anti-fungal medication related to clotrimazole (Lotrimin), ketoconazole (Nizoral), itraconazole (Sporanox), and miconazole (Micatin, Monistat). Fluconazole prevents growth of fungi by preventing production of the membranes that surround fungal cells.

What are the uses for Diflucan (fluconazole)?


Bowel regularity means a bowel movement every day.
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What are the side effects of Diflucan (fluconazole)?

Common side effects of fluconazole include

Other important side effects include

Possible serious side effects include

  • seizures,
  • reduced number of white blood cells,
  • reduced number of blood platelets, and
  • toxic epidermal necrolysis.

Rarely, serious allergic reactions, including angioedema (swelling of tissues), may also occur. Liver dysfunction (jaundice, hepatitis) and abnormal heart beats have been associated with fluconazole. Stevens-Johnson syndrome has also been reported.

What is the dosage for Diflucan (fluconazole)?

  • The usual adult dose is 50-400 mg daily depending on the type of infection. Although symptoms of oral Candida infections may subside in a few days, treatment is continued for 2 weeks.
  • Esophageal Candida infections are treated for 3 weeks or longer.
  • Treatment of cryptococcal meningitis may last for 10-12 weeks after cerebrospinal fluid cultures become negative.

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Which drugs or supplements interact with Diflucan (fluconazole)?

Is Diflucan (fluconazole) safe to use during pregnancy or while breastfeeding?

  • There are no adequate studies of Diflucan in pregnant women. There are reports of harmful effects to the fetus when high dose fluconazole was administered to pregnant women for a few months. Use of fluconazole during pregnancy is not recommended.
  • Diflucan is secreted in breast milk at concentrations similar to the mother's blood level. However, fluconazole is used for treating neonates with fungal infections and for treating lactation associated Candida infections. Available evidence suggests that use of fluconazole during breastfeeding has little risk.

What else should I know about Diflucan (fluconazole)?

Preparations available for Diflucan

  • Tablets: 50, 100, 150, and 200 mg.
  • Oral Suspension: 10 mg/ml and 40 mg/ml.
  • Injection: 2 mg/ml

How to keep Diflucan (fluconazole) stored

  • Tablets and dry powder should be stored below 86 F (30 C).Injection and reconstituted suspension should be stored between 5 C and 30 C (41 F and 86 F).
  • Unused portions of the reconstituted suspension should be protected from freezing and discarded after 2 weeks.

When was Diflucan (fluconazole) approved by the FDA?

  • The FDA approved fluconazole in January 1990.

Generic and prescription avialability

  • Diflucan is available in generic form. You need a prescription ffor Diflucan from your doctor.

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