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bepridil (Vascor): Angina Drug Uses, Side Effects & Dosage

What are the uses for bepridil?

Bepridil is prescribed for patients with angina pectoris (heart pain) due to coronary artery disease.

Vascor (bepridil hydrochloride) is indicated for the treatment of chronic stable angina (classic effort-associated angina). Because Vascor (bepridil) has caused serious ventricular arrhythmias, including torsades de pointes type ventricular tachycardia, and the occurrence of cases of agranulocytosis associated with its use (see WARNINGS), it should be reserved for patients who have failed to respond optimally to, or are intolerant of, other anti-anginal medication.

Vascor (bepridil) may be used alone or in combination with beta-blockers and/or nitrates. Controlled clinical studies have shown an added effect when Vascor (bepridil) is administered to patients already receiving propranolol.

Is bepridil available as a generic drug?


Do I need a prescription for bepridil?


What are the side effects of bepridil?

  • Bepridil can cause very serious cardiac arrhythmias. The risk is increased in patients with a specific electrocardiographic abnormality called QT prolongation and in patients with low blood concentrations of potassium or magnesium.
  • Bepridil also can cause increased or decreased heart rate and other abnormal rhythms.

Other side effects that can occur among patients taking bepridil include:

What is the dosage for bepridil?

Bepridil usually is taken once daily. It can be taken with meals or at bedtime if nausea is a problem.

Which drugs or supplements interact with bepridil?

Is bepridil safe to take if I’m pregnant or breastfeeding?

  • Bepridil crosses the placenta, and therefore should not be used
    pregnancy unless the benefit to the mother outweighs the potential but unknown risk to the fetus.
  • Bepridil is secreted into breast milk and therefore should not be used by
    breastfeeding mothers unless benefit to the mother clearly outweighs the potential but unknown risk to the infant.

What else should I know about bepridil?

What preparations of bepridil are available?

Tablets: 200 mg.

How should I keep bepridil stored?

Tablets should be stored at room temperature, 15C to 30 C (59 F to 86 F).


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