What is azelastine, and how does it work (mechanism of action)? Azelastine is an antihistamine, a chemical that blocks the effects of histamine, another chemical that is responsible for some of the symptoms in allergic reactions. Azelastine is chemically different from other antihistamines and is used only as a nasal inhaler for the treatment of …
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Meropenem (Merrem) Use, Side Effects & Interactions
What is meropenem injection, and how does it work (mechanism of action)? Meropenem is an injectable carbapenem antibiotic. It is similar to impenem and cilastin (Primaxin). Meropenem prevents bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without …
Read More »Propafenone (Rythmol) Uses, Side Effects & Dosage
What are the uses for propafenone? Propafenone is an anti-arrhythmic agent approved for use in patients with life-threatening ventricular arrhythmias, such as ventricular tachycardia. Propafenone is also effective in suppressing the recurrence of atrial fibrillation and supra-ventricular tachycardia once normal sinus rhythm has been restored. Propafenone is at least as effective as any other type I agent in converting atrial …
Read More »budesonide (Entocort EC, Uceris) for IBD: Side Effects & Dosage
What is budesonide (Entocort EC, Uceris)? Budesonide is a synthetic (man-made) steroid of the glucocorticoid family that is used for treating Crohn’s disease. What brand names are available for budesonide? Entocort EC and Uceris are brand names for budesonide in the US. Why is budesonide (Entocort EC, Uceris) prescribed to patients? Budesonide is used for the treatment of mild-to-moderately-active Crohn’s …
Read More »Octreotide (Sandostatin) Uses, Side Effects & Dosage
What is octreotide injection, and how does it work (mechanism of action)? Octreotide acetate is an injectable medicine that is very similar to the hormone somatostatin, which is naturally produced in the body that has several effects including inhibition of the release of hormones. Octreotide works in a similar fashion as somatostatin, but is degraded more slowly and is a …
Read More »bupivacaine (Marcaine, Sensorcaine) Side Effects & Dosage
What is bupivicaine injection, and how does it work (mechanism of action)? Bupivacaine is a local anesthetic that is similar to lidocaine and mepivacaine (amide type). Bupivacaine, like other local anesthetics reduces the flow of sodium in and out of nerves. This decreases the initiation and transfer of nerve signals in the area in which the drug is applied. This …
Read More »Nadolol (Corgard) Uses, Side Effects & Dosage
What is nadolol, and how does it work (mechanism of action)? Nadolol is a member of a class of drugs called beta-adrenergic receptor blockers that is used for treating high blood pressure and heart pain (angina). Examples of other beta-adrenergic blockers include propanolol (Inderal, Inderal LA), atenolol (Tenormin), and timolol (Blocadren). Norepinephrine and epinephrine (adrenaline) are chemicals released within the …
Read More »Rogaine (minoxidil) Hair-Loss Ointment Results for Men & Women
What is minoxidil, and how does it work (mechanism of action)? Minoxidil is a drug that is used for treating male-pattern baldness and hair loss in women. Oral minoxidil was originally used for treating high blood pressure, but patients and health care providers noticed that hair growth was a side effect of treatment. This led to the development of topical …
Read More »mannitol (Osmitrol) Uses, Side Effects & Dosage
What is mannitol, and how does it work (mechanism of action)? Mannitol is a naturally occurring substance that causes the body to lose water (diuresis) through osmosis. Mannitol promotes diuresis in kidneys by increasing the concentration of filtrates in the kidney and blocking reabsorption of water by kidney tubules. The FDA approved mannitol in June 1964. What brand names are …
Read More »Atovaquone/Proguanil (Malarone) Uses Side Effects & Dosage
What is atovaquone-proguanil, and how does it work (mechanism of action)? Atovaquone and proguanil is an anti-malarial medication. Atovaquone blocks mitochondrial electron transfer and thereby the production of energy for use by the parasites. Proguanil is metabolized into its active metabolite, cycloguanil, which blocks dihydrofolate reductase and enzymes required for making pyrimidine which is a chemical needed for production of …
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