What is brimonidine, and how does it work (mechanism of action)? Brimonidine is is an ophthalmic solution used for the treatment of one type of glaucoma, open-angle glaucoma. In this type of glaucoma, too much fluid (aqueous humor) is made within the eye and causes high pressures within the eye. The pressure damages the nerves …
Read More »
What is leflunomide, and how does it work (mechanism of action)? Leflunomide is an oral, disease-modifying drug that is used in the treatment of rheumatoid arthritis. Leflunomide reduces inflammation in the joints that is responsible for both the symptoms of rheumatoid arthritis and the destruction of joints. This reduces symptoms as well as the progressive deformities of the joints caused …
Read More »
What is avanafil (Stendra), and how does it work (mechanism of action)? Avanafil is an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection), also known as erectile dysfunction (ED). It is in a class of drugs called phosphodiesterase inhibitors that also includes tadalafil (Cialis), sildenafil (Viagra) and vardenafil (Levitra). Erection of …
Read More »
What is isosorbide dinitrate, and how does it work (mechanism of action)? Isosorbide dinitrate is in the class of drugs called nitrates, and it is used for treating and preventing angina or heart pain. Other nitrates include nitroglycerin (Nitrostat, Nitroquick, Nitrolingual, Nitro-Dur and others) and isosorbide mononitrate (Imdur, Ismo, Monoket). Isosorbide dinitrate is converted in the body to isosorbide mononitrate …
Read More »
What is azelastine, and how does it work (mechanism of action)? Azelastine is an antihistamine, a chemical that blocks the effects of histamine, another chemical that is responsible for some of the symptoms in allergic reactions. Azelastine is chemically different from other antihistamines and is used only as a nasal inhaler for the treatment of symptoms of seasonal allergic rhinitis, …
Read More »
What is triazolam, and how does it work (mechanism of action)? Triazolam is a drug that is used to promote sleep in individuals who have difficulty sleeping (insomnia). It is in the benzodiazepine family of drugs, the same family that includes diazepam (Valium), alprazolam (Xanax), clonazepam (Klonopin), flurazepam (Dalmane), lorazepam (Ativan), and others. Insomnia is believed often to be the …
Read More »
What is levocarnitine, and how does it work (mechanism of action)? Levocarnitine (Carnitor) is a naturally occurring substance that the cells of mammals need to produce energy. It is used to treat carnitine deficiency. Carnitine is a small protein that binds to and helps transport fatty acids into the mitochondria, the site of energy production within cells. In the mitochondria, …
Read More »
What is latanoprost, and how does it work (mechanism of action)? Latanoprost, a derivative of the chemical, prostaglandin F2-alpha, is used for the treatment of glaucoma. Glaucoma is a condition in which the pressure exerted by the liquid within the eyeball (the aqueous humor) is too great. The high pressure damages the optic nerve at the back of the eye. …
Read More »
What is tetracycline, and how does it work (mechanism of action)? Tetracycline is a broad spectrum antibiotic, that is, it is active against many different types of bacteria. It is effective against Hemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydia psittaci, Chlamydia trachomatis, Neisseria gonorrhoeae, and many others. Tetracycline prevents growth of bacteria by preventing the bacteria from manufacturing proteins that …
Read More »
What is metolazone, and how does it work (mechanism of action)? Metolazone is a diuretic ("water pill") used in the treatment of high blood pressure and fluid accumulation. It works by blocking salt and fluid retention by the kidneys, thereby increasing urinary output of salt and water (diuresis). Although it is not a true thiazide, metolazone is chemically related to …
Read More »