What is tocilizumab, and how does it work (mechanism of action)? Tocilizumab is an injectable synthetic (man-made) protein that binds to interleukin-6 (IL-6) in the body and blocks the effects of IL-6 in patients with rheumatoid arthritis. Inflammation is the body's reaction to injury and is a necessary process for the repair of injury. IL-6 …

Rhabdomyolysis facts What Is Rhabdomyolysis? Rhabdomyolysis is the rapid destruction of skeletal muscle resulting in leakage into the urine of the muscle protein myoglobin. Rhabdomyolysis has many causes. Medications can cause muscle injury and rhabdomyolysis. Rhabdomyolysis can cause muscle pain and weakness. Blood levels of muscle enzymes, including CPK, SGOT, SGPT, and LDH, as well as blood and urine myoglobin …

What are sexual problems in men? Sexual problems in men also affect their partners. Sexual health is an important part of a man's life, no matter his age, civil status, or sexual orientation. It is also an important part of a couple's foundation and contributes to the quality of life. Sexual problems in men are very common and impact sexual …

Deviated septum surgery (septoplasty) and turbinectomy facts Picture of the anatomy of the sinuses The following information is provided to help patients and their families prepare for deviated septum surgery (septoplasty) and turbinectomy (nasal airway surgery), and to understand more clearly the associated benefits, risks, and complications. Patients are encouraged to ask their doctor any questions or concerns to help …

Malaria facts Picture of Malaria Precautions by Sleeping Under Mosquito Nets Treated with Insecticide More than 215 million cases of malaria occurred worldwide in 2016. The World Health Organization estimates that 445,000 people died of malaria in 2016; the vast majority are young children in sub-Saharan Africa. Although this is a significant decrease in deaths since 2000 due to increased …

Magnetic resonance imaging (MRI) scan definition and facts Readers Comments 17 Share Your Story Picture: A medical technician prepares a patient for an MRI to check for a possible brain tumor Magnetic resonance imaging or MRI scanning uses magnetism, radio waves, and a computer to produce images of body structures. MRI scanning is painless and does not involve x-ray radiation. …

What is zonisamide-oral, and how does it work (mechanism of action)? Scientists do not known how exactly zonisamide works in the body. Zonisamide is presumed to work on the sodium and calcium channels in the brain cells where it controls electric-currents that are responsible for seizure activity. The FDA approved zonisamide in March 2000. The brand name for zonisamide is …

What is Savella (milnacipran)? How does it work (mechanism of action)? Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for treating pain associated with fibromyalgia. It is similar to duloxetine (Cymbalta), venlafaxine (Effexor), and desvenlafaxine (Pristiq). Milnacipran affects neurotransmitters, the chemicals that nerves within the brain make and release in order to communicate with one another. Neurotransmitters …

What is sodium polystyrene sulfonate-powder? How does it work (mechanism of action)? Sodium polystyrene sulfonate is a cation-exchange resin taken orally that is used to reduce high levels of potassium in the blood (hyperkalemia). Sodium polystyrene sulfonate removes potassium by exchanging sodium ions for potassium ions in the intestine. The majority of this cation exchange seems to take place in …

What is Lyrica (pregabalin)? Lyrica (pregabalin) is an oral medication that is chemically related to gabapentin (Gralise, Neurontin). It is used for treating pain caused by neurologic diseases such as postherpetic neuralgia as well as seizures. It also is used for treating fibromyalgia. Is Lyrica (pregabalin) available as a generic drug? Yes Do I need a prescription for Lyrica (pregabalin)? …