tizanidine (Zanaflex) Side Effects, Dosage & Abuse

What is tizanidine-oral, and how does it work (mechanism of action)?

Tizanidine is a skeletal muscle
relaxant. It works on alpha2 receptors in the central nervous system (brain and
spinal cord) and blocks nerve impulses from reaching muscles which produces
muscle relaxation. The FDA approved tizanidine in November 1996.

What brand names are available for tizanidine-oral?


Is tizanidine-oral available as a generic drug?


Do I need a prescription for tizanidine-oral?


What are the uses for tizanidine-oral?

Tizanidine is used for the treatment and
management of skeletal muscle spasticity. Spasticity may be due to multiple
sclerosis or spinal cord injury.

What are the side effects of tizanidine-oral?

Common side effects of tizanidine include:

What is the dosage for tizanidine-oral?

Initially take 2 – 4 mg by mouth every 6 to 8 hours
for up to 3 doses in 24 hours. Increase by 2 to 4 mg until satisfactory response
is achieved; however, the maximum dose is 36 mg per day.

Which drugs or supplements interact with tizanidine-oral?

Tizanidine should not be used with:

These medications
can slow down the breakdown of tizanidine and lead to increased sedation,
drowsiness and slowed reflexes.

Tizanidine should be used with caution with medications like:

These medications can further increase the side effects of tizanidine.

Is tizanidine-oral safe to take if I’m pregnant or breastfeeding?

There are no adequate studies done on tizanidine to determine safe and effective use in pregnant women.

It is not known whether tizanidine enters human milk. Because it is soluble in lipids, it might pass into
breast milk.

What else should I know about tizanidine-oral?

What preparations of tizanidine-oral are available?

Capsules: 2, 4, 6 mg; Tablets: 2, 4 mg

How should I keep tizanidine-oral stored?

Store tizanidine tablets and capsules between
temperatures of 15 C – 30 C (59 F – 86 F).

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