What is amitriptyline w/ perphenazine-oral, and how does it work (mechanism of action)? Perphenazine/amitriptyline is a combination of an antipsychotic and an antidepressant. Perphenazine is an antipsychotic that works in the brain and nervous system. Its exact mechanism of action is unknown. Amitriptyline is a tricyclic antidepressant. It is believed that in some patients with …
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What is dalfampridine, Ampyra, and how does it work (mechanism of action)? Ampyra is an oral medication used for treating multiple sclerosis (MS). Its exact mechanism of action is unknown, but it is known to block movement of potassium between nerve cells. In animal studies Ampyra increased the conduction of nerve signals. The FDA approved Ampyra in December 1987. What …
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What is pramoxine, and how does it work (mechanism of action)? Pramoxine is a topical (used on the skin) anesthetic (numbing agent). Topical anesthetics are chemicals that interfere with the function of the nerves that sense pain. Pramoxine may be used in persons who are allergic to other local anesthetics such as lidocaine, procaine, or benzocaine. Is it available as …
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What is rofecoxib, and how does it work (mechanism of action)? Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain, particularly the pain of osteoarthritis and menstrual cramps. Prostaglandins are chemicals that are important in promoting inflammation and its signs–pain, fever, swelling and tenderness. Rofecoxib blocks the enzyme that makes prostaglandins (cyclooxygenase- 2) and thereby reduces …
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What is dextroamphetamine-oral capsule, tablet, and how does it work (mechanism of action)? Dextroamphetamine is a medication used for treating attention-deficit hyperactivity disorder (ADHD) and narcolepsy. ADHD is a common disorder among children and teenagers that affects social, academic, and occupational functioning. Narcolepsy also is known as excessive daytime sleepiness, which is more common in adults. Dextroamphetamine is an amphetamine …
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What is dimethyl fumarate, and how does it work (mechanism of action)? Dimethyl fumarate is an oral disease-modifying agent used for treating relapsing forms of multiple sclerosis (MS). Teriflunomide (Aubagio), Interferon beta-1a (Avonex), interferon beta-1b (Betaseron), glatiramer acetate (Copaxone), interferon beta-1b (Extavia), fingolimod (Gilenya), mitoxantrone (Novantrone), interferon beta-1a (Rebif), and natalizumab (Tysabri) are other disease modifying agents for multiple sclerosis. …
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What is loracarbef, and how does it work (mechanism of action)? Loracarbef is a synthetic oral antibiotic in the cephalosporin family of antibiotics. The cephalosporin family includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefprozil (Cefzil), and many injectable antibiotics. Like other cephalosporins, loracarbef stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The …
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What is clonidine (Kapvay extended-release), and how does it work (mechanism of action)? Kapvay is an oral medication used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents. This drug has been used to reduce blood pressure in adults for many years but has been approved for another indication by the FDA. Kapvay works by stimulating alpha-2 receptors …
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What is methylphenidate hydrochloride, and how does it work (mechanism of action)? Methylphenidate is a medication used for treating attention deficit hyperactivity disorder (ADHD). It stimulates the central nervous system (CNS or brain) in a manner that is similar to amphetamines; however, its actions are milder than amphetamines. Amphetamines stimulate the brain by increasing the level of neurotransmitters, dopamine and …
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What is apremilast, and how does it work (mechanism of action)? Apremilast is an oral medication used to treat adults with active psoriatic arthritis (a form of arthritis that affects some people with psoriasis). It is also used to treat moderate to severe plaque psoriasis in patients who are candidates for phototherapy or systemic therapy. Apremilast works by reducing production …
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