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HomeUncategorizedIs Pustular Psoriasis an Autoimmune Disease? Causes & Risk Factors

Is Pustular Psoriasis an Autoimmune Disease? Causes & Risk Factors

Pustular Psoriasis
Pustular psoriasis is an autoimmune disease.

Yes, psoriasis pustulosa is an uncommon immune-mediated systemic skin ailment that is characterized by yellowish pustules over the skin on an erythematous base. This condition may present clinically in several ways and have a range of distribution patterns. 

Psoriasis pustulosa is regarded as a subtype of the more common psoriasis vulgaris. The pustules may be extensive or localized, and they are distinguished by a sterile (noninfective) infiltration that is mostly composed of neutrophils.

Pustular psoriasis is a skin disorder. You'll see white pimple-like lesions that are loaded with pus around or within red spots on the skin, which are medically known as pustules They have the potential to be painful and scaly, flaky, or irritating. It is most likely to have an impact on:

  • Your palms when they are open.
  • The bottoms of both of your feet.
  • Your digits, both big and little.

Pus is made up of white blood cells and does not indicate the presence of an infection. The parts that are impacted will look reddened on those with light skin. The spots seem to have a darker hue on those with darker skin. The symptoms of generalized pustular psoriasis, also known as von Zumbusch psoriasis, may be seen almost everywhere on the body.

What is generalized pustular psoriasis?

The condition known as generalized pustular psoriasis (GPP) displays itself extensively on parts of the body.

  • Fever, chills, intense itching, a change in heart rate, exhaustion, and muscular weakness are common symptoms of GPP, which may come on abruptly and advance swiftly. GPP can also develop suddenly and quickly. If you suspect you have GPP, you should seek medical attention as soon as possible.
  • Blotches of skin that are red, sore, and sensitive appear across a large portion of your body, and shortly afterward, blisters that are filled with pus appear. Your skin may experience severe itching. You may also experience extreme fatigue, dehydration, nausea, headache, joint pain, rapid heart rate, or weight loss. This is a very uncommon and potentially fatal illness. If you are experiencing any of these symptoms, you should seek medical attention immediately.

Palmoplantar pustulosis

Blisters occur on tiny parts of your body, most often on your palms or the soles of your feet, when you have palmoplantar pustulosis, also known as PPP. These pus-filled bumps may become brown, flake off, or crust over at some point. Even your skin is susceptible to cracking. This particular kind of psoriasis may appear and disappear at will. People who smoke have a greater risk of developing this version of the disease.


It is a condition in which little, very painful sores appear on the tips of your fingers or toes. Because of the discomfort, it may be difficult for you to use your fingers or toes. In very unusual instances, it may potentially cause injury to the bone or the nail.

What are the causes of pustular psoriasis?

Psoriasis is an autoimmune illness. White blood cells are typically the cells that are sent by your immune system to fight against sickness in your body. In this particular instance, though, they make the mistake of attacking your own skin.

Psoriasis outbreaks may be triggered by a number of different reasons, including:

  • Pharmaceuticals, such as anabolic steroids
  • Something that causes your skin to become irritated, such as a topical cream or a skin care treatment that is too strong
  • Excessive exposure to the sun
  • Stress

Risk factors associated with pustular psoriasis

Psoriasis pustulosa seems to be triggered by a number of different factors, including the following:

  • The use of some internal drugs, such as corticosteroids, or the discontinuation of their usage
  • The use of certain topical creams
  • Excessive exposure to ultraviolet radiation, such as that from sunshine

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