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doxycycline (Vibramycin, Doryx) Side Effects, Dosage & Uses

Do I need a prescription for doxycycline?


What is doxycycline?

Doxycycline is a synthetic (man-made) antibiotic derived from tetracycline.

What brand names are available for doxycycline?

Brand names for doxycycline hyclate include Vibramycin, Oracea, Adoxa, Atridox, Acticlate, Acticlate Cap, Doryx, Doxteric, Doxy, Monodox, and others.

Is doxycycline available as a generic drug?


Why is doxycycline prescribed to patients?

Doxycycline is used for many different types of infections, including respiratory tract infections due to Hemophilus influenzae, Streptococcus pneumoniae, or Mycoplasma pneumoniae. It also is used for the treatment of

What are the side effects of doxycycline?

Doxycycline is generally well-tolerated. The most common
side effects are

Tetracyclines, such as doxycycline, may cause tooth discoloration if used in persons below 8 years of age. Exaggerated
sunburn can occur with tetracyclines; therefore,
sunlight should be
minimized during treatment.


Bowel regularity means a bowel movement every day.
See Answer

What is the dosage for doxycycline?

  • The absorption of doxycycline is not markedly affected by food, and
    therefore, it can be taken with meals.
  • For most infections, doxycycline is taken
    once or twice daily for 7 to 14 days.
  • For adult infections, the usual dose of
    oral doxycycline is 200 mg on the first day of treatment (100 mg every 12 hours)
    followed by a dose of 100 to 200 mg/day as a single dose or divided and
    administered twice daily.

Which drugs or supplements interact with doxycycline?

  • It is recommended that doxycycline
    not be taken at the same time as aluminum, magnesium, or calcium based antacids, such as
    Mylanta, Maalox, Tums, or Rolaids because, like food, these medications bind doxycycline in the
    intestine and prevent its absorption. Similarly, doxycycline should not be taken
    with minerals (such as calcium or iron) or with

    bismuth subsalicylate (Pepto Bismol).

  • Doxycycline may enhance the activity of
    (Jantoven, Coumadin) and cause excessive "thinning" of the blood leading to exaggerated
    bleeding, necessitating a reduction in the dose of warfarin.
    Phenytoin (Dilantin),
    (Tegretol), and
    barbiturates (such as phenobarbital) may enhance the metabolism
    (destruction) of doxycycline thus making it less effective.
  • Doxycycline may interfere with the action of penicillins and should not be
    combined with penicillins. It may also reduce the effect of
    oral contraceptives.
    Combining tetracycline and methoxyflurane (Penthrane) may reduce kidney

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Is doxycycline safe to use during pregnancy or while breastfeeding?

  • Tetracycline antibiotics, such as doxycycline, can have toxic
    effects on development of bone in the fetus. Therefore, tetracyclines are not
    during pregnancy unless there is no other appropriate antibiotic.
  • Doxycycline is secreted into
    breast milk
    but the extent of absorption by the breastfed infant is not known. Since tetracyclines can cause toxic effects on bone, the use of tetracyclines in
    nursing mothers is of concern. The physician must decide whether to recommend
    that a nursing mother discontinue nursing during treatment with tetracyclines or
    change to a different antibiotic.

What else should I know about doxycycline?

What preparations of doxycycline are available?
  • Capsules: 50, 75, 100 and 150 mg.
  • Capsule (Delayed Release): 40 mg.
  • Tablets: 20, 50, 75, 100 and
    150 mg.
  • Tablets (Delayed Release): 50, 60, 75, 80, 100, 120, 150, and 200 mg.
  • Syrup: 50 mg/5 ml (teaspoon)
  • Oral Suspension: 25 mg/5ml
  • Powder for injection: 100and 200 mg.
  • Periodontal Extended Release Liquid: 10%
How should I keep doxycycline stored?
  • Tablets, capsules, and syrup should be kept at room temperature 15 C
    to 30 C (59 F to 86 F) in tight, light resistant containers.
  • Powder for injection should be stored at or below 25 C (77 F) and protected
    from light.
  • Atridox (doxycycline in a gel used for subgingival application) should be
    stored at 2 C to 8 C (36 F to 46 F).
How does doxycycline work?
  • Doxycycline works by interrupting the production of proteins
    by bacteria. It is effective against a wide variety of bacteria, such as
    Hemophilus influenzae,

    pneumoniae, Mycoplasma pneumoniae, Chlamydia psittaci,
    Chlamydia trachomatis, Neisseria gonorrhoea
    , and many
When was doxycycline approved by the FDA?

The FDA approved doxycycline in December 1967.


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