What is docetaxel, and how does it work (mechanism of action)? Docetaxel is a drug that is used primarily for treating breast cancer. Docetaxel works by attacking cancer cells. Every cell in the body contains a supporting structure (almost like a skeleton) called the microtubular network. If this "skeleton" is changed or damaged, the cell …
Read More »cancer
Throat Cancer (Larynx Cancer) Symptoms, Causes, Survival Rate
Throat cancer (larynx cancer) facts* Readers Comments 33 Share Your Story HPV infection, cigarette smoking, alcoholism, and asbestos exposure are risk factors for throat cancer. *Throat cancer (larynx cancer) facts author: Melissa Conrad Stöppler, MD The larynx is the voice box located at the top of the windpipe (trachea). Cancer of the larynx occurs most often in people over the …
Read More »lenalidomide (Revlimid): Cancer Drug Side Effects & Dosage
What is lenalidomide (Revlimid)? What is lenalidomide used for? Lenalidomide (Revlimid) is an oral anti-cancer medication. Lenalidomide is similar to thalidomide (Thalomid), an older cancer medicine that, although effective, was associated with serious side effects. The exact mechanism through which lenalidomide stops the growth of cancer cells is not understood. Lenalidomide stimulates or regulates the body’s immune system to attack …
Read More »Imatinib (Gleevec): Leukemia Drug Side Effects & Dosage
What is imatinib, and how does it work (mechanism of action)? Imatinib is an oral medication used for treating chronic myeloid leukemia and acute lymphoblastic leukemia. It is classified as a kinase inhibitor. Kinase inhibitors include dasatinib (Sprycel), erlotinib (Tarceva), gefitinib (Iressa), nilotinib (Tasigna), pazopanib (Votrient), sunitinib (Sutent), and vandetanib (Caprelsa). Kinase inhibitors prevent tumors from growing by reducing the …
Read More »sodium iodide I 131, Iodotope, Sodium Iodide I 131 Therapeutic: Drug Facts, Side Effects and Dosing
What is sodium iodide I 131, and how does it work (mechanism of action)? Sodium iodide I 131 is an oral medication used to treat hyperthyroidism (overactive thyroid gland) and some cases of thyroid cancer. It falls under the category of an anti-thyroid drug but differs from the other anti-thyroid drugs, propylthiouracil (PTU) and methimazole (Tapazole), because it is radioactive. …
Read More »megestrol (Megace, Megace ES): Drug Facts, Side Effects & Dosage
What is megestrol, and how does it work (mechanism of action)? Megestrol is a synthetic female hormone belonging to the progesterone group. It is used for stimulating appetite and treating breast cancer. Progesterone is a hormone produced by the body, especially in women, that helps control the menstrual period as well as other body functions. How megestrol stimulates appetite or …
Read More »Xeloda (capecitabine): Cancer Drug Facts, Side Effects and Dosage
What is capecitabine (Xeloda), and how does it work (mechanism of action)? Capecitabine is an oral medication for treating advanced breast cancer that is resistant to combination therapy with the drugs of choice, paclitaxel (Taxol) and a drug from the anthracycline family of drugs, for example, doxorubicin (Adriamycin). Capecitabine is converted by the body to 5-fluorouracil (5-FU), a drug which …
Read More »Triple-Negative Breast Cancer Symptoms, Causes, Survival Rate, Recurrence
Facts you should know about triple-negative breast cancer Share Your Story Picture of Breast Cancer Symptoms Triple-negative breast cancer is an uncommon kind of breast cancer in which the cancer cells test negative for three common markers, the estrogen receptor (ER), progesterone receptor (PR), and a protein involved in cell growth known as HER2. The triple-negative status of a cancer …
Read More »Ondansetron (Zofran): Anti-Nausea Drug Side Effects & Interactions
What is ondansetron oral disintegrating tablet, and how does it work (mechanism of action)? Ondansetron is an anti-nausea medication most often used to prevent nausea and vomiting caused by chemotherapy. Chemotherapy agents increase secretion of serotonin which stimulates serotonin (5-HT3) receptors in the brain, causing nausea and vomiting. Ondansetron works by selectively blocking serotonin (5-HT3) receptors, reducing the effect of …
Read More »dronabinol (Marinol, THC): Side Effects and Dosing
What is dronabinol-oral, and how does it work (mechanism of action)? Dronabinol (Marinol) is a man-made compound that contains cannabinoids found in the marijuana plant (Cannabis sativa L). Dronabinol contains tetrahydrocannabinol (THC) in standardized concentrations and does not contain other compounds found in street marijuana that is not approved by the FDA for medical use. Dronabinol activates cannabinoid receptors causing …
Read More »