cancer

What is nilotinib? What is nilotinib used for? Nilotinib is an oral medication used for treating chronic myeloid leukemia and acute lymphoblastic leukemia. Nilotinib is classified as a kinase inhibitor. Kinase inhibitors include dasatinib (Sprycel), erlotinib (Tarceva), gefitinib (Iressa), imatinib (Gleevec), pazopanib (Votrient), sunitinib (Sutent), and vandetanib (Caprelsa). Kinase inhibitors prevent the growth of tumors …

What is sargramostim, and how does it work (mechanism of action)? Sargramostim is a man-made form of the naturally-occurring protein, granulocyte, macrophage-colony stimulating factor (GM-CSF). GM-CSF is produced in the body by the immune system and stimulates the formation of white blood cells, including the granulocyte and the macrophage. Granulocytes and macrophages take part in the inflammatory reaction. They are …

What is docetaxel, and how does it work (mechanism of action)? Docetaxel is a drug that is used primarily for treating breast cancer. Docetaxel works by attacking cancer cells. Every cell in the body contains a supporting structure (almost like a skeleton) called the microtubular network. If this "skeleton" is changed or damaged, the cell can't grow or reproduce. Docetaxel …

What is imatinib, and how does it work (mechanism of action)? Imatinib is an oral medication used for treating chronic myeloid leukemia and acute lymphoblastic leukemia. It is classified as a kinase inhibitor. Kinase inhibitors include dasatinib (Sprycel), erlotinib (Tarceva), gefitinib (Iressa), nilotinib (Tasigna), pazopanib (Votrient), sunitinib (Sutent), and vandetanib (Caprelsa). Kinase inhibitors prevent tumors from growing by reducing the …

What is sodium iodide I 131, and how does it work (mechanism of action)? Sodium iodide I 131 is an oral medication used to treat hyperthyroidism (overactive thyroid gland) and some cases of thyroid cancer. It falls under the category of an anti-thyroid drug but differs from the other anti-thyroid drugs, propylthiouracil (PTU) and methimazole (Tapazole), because it is radioactive. …

What is megestrol, and how does it work (mechanism of action)? Megestrol is a synthetic female hormone belonging to the progesterone group. It is used for stimulating appetite and treating breast cancer. Progesterone is a hormone produced by the body, especially in women, that helps control the menstrual period as well as other body functions. How megestrol stimulates appetite or …

What is capecitabine (Xeloda), and how does it work (mechanism of action)? Capecitabine is an oral medication for treating advanced breast cancer that is resistant to combination therapy with the drugs of choice, paclitaxel (Taxol) and a drug from the anthracycline family of drugs, for example, doxorubicin (Adriamycin). Capecitabine is converted by the body to 5-fluorouracil (5-FU), a drug which …

Facts you should know about triple-negative breast cancer Share Your Story Picture of Breast Cancer Symptoms Triple-negative breast cancer is an uncommon kind of breast cancer in which the cancer cells test negative for three common markers, the estrogen receptor (ER), progesterone receptor (PR), and a protein involved in cell growth known as HER2. The triple-negative status of a cancer …

What is ondansetron oral disintegrating tablet, and how does it work (mechanism of action)? Ondansetron is an anti-nausea medication most often used to prevent nausea and vomiting caused by chemotherapy. Chemotherapy agents increase secretion of serotonin which stimulates serotonin (5-HT3) receptors in the brain, causing nausea and vomiting. Ondansetron works by selectively blocking serotonin (5-HT3) receptors, reducing the effect of …

What is dronabinol-oral, and how does it work (mechanism of action)? Dronabinol (Marinol) is a man-made compound that contains cannabinoids found in the marijuana plant (Cannabis sativa L). Dronabinol contains tetrahydrocannabinol (THC) in standardized concentrations and does not contain other compounds found in street marijuana that is not approved by the FDA for medical use. Dronabinol activates cannabinoid receptors causing …