What is bicalutamide, and how does it work (mechanism of action)? Bicalutamide is an oral medication that is used for treating cancer of the prostate. It belongs to a class of drugs called anti-androgens which includes flutamide (Eulexin) and nilutamide (Nilandron). Androgens (an example of which is testosterone) are hormones that are produced and released …
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What is tamoxifen (Soltamox)? Tamoxifen is an anti-estrogen that prevents the effects of estrogens on tissues. What brand names are available for tamoxifen (Soltamox)? Soltamox is currently the only brand available for tamoxifen. Nolvadex brand has been discontinued. Is tamoxifen (Soltamox) available as a generic drug? Yes Do I need a prescription for tamoxifen (Soltamox)? Yes Why is tamoxifen (Soltamox) …
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What is hydroxyurea, and how does it work (mechanism of action)? Hydroxyurea (Hydrea) is an oral medication used to treat several types of cancers including chronic myelogenous leukemia (CML), acute myelogenous leukemia (AML), head and neck cancer, malignant melanoma, ovarian cancer, and polycythemia vera (a disorder of the bone marrow). The exact mechanism by which hydroxyurea works to treat cancer …
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What is leuprolide, and how does it work (mechanism of action)? Leuprolide is an injectable, man-made hormone that is used for treating prostate cancer, endometriosis, central precocious puberty (early onset of puberty), and fibroids. It is similar to but stronger than human gonadotropin releasing hormone (GnRH). GnRH is made in the hypothalamus (a part of the brain) and travels to …
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What is letrozole, and how does it work (mechanism of action)? Letrozole is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the …
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What is octreotide injection, and how does it work (mechanism of action)? Octreotide acetate is an injectable medicine that is very similar to the hormone somatostatin, which is naturally produced in the body that has several effects including inhibition of the release of hormones. Octreotide works in a similar fashion as somatostatin, but is degraded more slowly and is a …
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What is Optune, and what is it used for? Optune is a treatment for adult patients (22 years of age or older). Optune is used after surgery, and radiation with chemotherapy have been used if possible. A doctor may use Optune to treat a patient with newly diagnosed brain cancer (called glioblastoma multiforme, or “GBM”) in the higher parts of …
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Dilaudid vs. Percocet quick comparison Dilaudid (hydromorphone hydrochloride) and Percocet (oxycodone and acetaminophen) are both opioid narcotic pain relievers. Percocet has an additional non-narcotic pain reliever added (acetaminophen) which achieves greater pain relief than either drug taken separately. Both Dilaudid and Percocet are available as generic drugs. Side effects of both Dilaudid and Percocet are similar and include lightheadedness, dizziness, …
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What is lapatinib (Tykerb), and how is it used? Tykerb is indicated in combination with: capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress human epidermal growth factor receptor 2 (HER2) and who have received prior therapy including an anthracycline, a taxane, and trastuzumab. Limitation of Use: Patients should have disease progression on trastuzumab …
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What is rituximab? How does it work (mechanism of action)? Rituximab is an intravenous drug that is used to treat rheumatoid arthritis and B-cell non-Hodgkin's lymphoma. It belongs to a class of drugs called monoclonal antibodies. Other monoclonal antibodies include trastuzumab (Herceptin) and gemtuzumab ozogamicin (Mylotarg). Tumor cells (like most normal cells) have receptors on their surfaces. Many kinds of …
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