What is heparin, and how does it work (mechanism of action)? Heparin is a widely used injectable anticoagulant (stops the formation of blood clots). The blood coagulation system is composed of various steps and heparin acts at multiple sites in this process. Heparin prevents blood clots by blocking the action of two of the 12 …
Read More »Prednisolone (Orapred, Pediapred) Uses, Side Effects & Dosage
What is prednisolone, and how does it work (mechanism of action)? Prednisolone is a synthetic adrenal corticosteroid (cortisone). Corticosteroids are natural substances produced by the adrenal glands located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties, and are used in a wide variety of inflammatory conditions such as arthritis, colitis, asthma, bronchitis, certain skin rashes, and allergic or inflammatory …
Read More »Oral Cyanocobalamin (Vitamin B12) Side Effects & Dosage
What is cyanocobalamin tablets, and how does it work (mechanism of action)? Cyanocobalamin or vitamin B12 is an essential B-vitamin that is classified as a water-soluble vitamin. Food sources of vitamin B12 include fish, shellfish, meats, and dairy products. Vitamin B12 is necessary for growth, reproduction of cells (for example, production of red blood cells, and the production of myelin …
Read More »cilostazol (Pletal) Uses, Side Effects & Dosage
What is cilostazol, and how does it work (mechanism of action)? Cilostazol is a medication for the treatment of intermittent claudication, a condition caused by narrowing of the arteries that supply the legs with blood. Patients with intermittent claudication develop pain when they walk because not enough oxygen-containing blood reaches the active leg muscles. Cilostazol reduces the pain of intermittent …
Read More »Calcium Acetate (Phoslo): Uses, Dosage & Side Effects
What is calcium acetate, and how does it work (mechanism of action)? Calcium acetate helps reduce phosphate levels in people with advanced kidney disease. People with advanced kidney failure retain phosphate leading to too much phosphate in their bodies (hyperphosphatemia). High phosphate levels cause hyperparathyroidism, which leads to abnormal bone formation and calcium deposits in tissues. Calcium acetate is a …
Read More »bicalutamide (Casodex) Uses, Side Effects & Dosage
What is bicalutamide, and how does it work (mechanism of action)? Bicalutamide is an oral medication that is used for treating cancer of the prostate. It belongs to a class of drugs called anti-androgens which includes flutamide (Eulexin) and nilutamide (Nilandron). Androgens (an example of which is testosterone) are hormones that are produced and released by the adrenal glands. They …
Read More »benazepril (Lotensin) Uses, Side Effects & Dosage
What is benazepril, and how does it work (mechanism of action)? Benazepril is an ACE (angiotensin converting enzyme) inhibitor used for treating high blood pressure. Other ACE inhibitors include enalapril (Vasotec), quinapril (Accupril), captopril (Capoten), fosinopril (Monopril), ramipril (Altace), moexipril (Univasc) and trandolapril (Mavik). ACE is an enzyme in the body that causes the formation of angiotensin II. Angiotensin II …
Read More »Diclofenac/Misoprostol (Arthrotec) Uses, Side Effects & Dosage
What is diclofenac and misoprostol, and how does it work (mechanism of action)? Arthrotec is a combination of diclofenac and misoprostol. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) similar to ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others that is used to treat inflammation, pain, and fever. Diclofenac, like other NSAIDs works by inhibiting the production of prostaglandins. Prostaglandins are …
Read More »amlodipine & valsartan (Exforge) Uses, Side Effects & Dosage
What is amlodipine and valsartan, and how does it work (mechanism of action)? Exforge is a combination of two drugs used for treating high blood pressure (hypertension), amlodipine and valsartan. The FDA approved Exforge in June 2007. Amlodipine belongs to a class of drugs called calcium channel blockers. These medications block the transport of calcium into the smooth muscle cells …
Read More »Hepatitis E Symptoms, Transmission, and Prevention
What should I know about hepatitis E (hep E) viral infection? Share Your Story Picture of Hepatitis Virus by Ingram Publishing, Medical RF.com Hepatitis E is a viral infection, which is caused by the hepatitis E virus that usually comes from dirty water. Hep E is uncommon in the U.S., Canada, Northern Europe, and Australia and very uncommon in the …
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