What is cimetidine, and how does it work (mechanism of action)? Cimetidine is a drug that blocks the production of acid by acid-producing cells in the stomach and can be administered orally, IM or IV. It belongs to a class of drugs called H2 (histamine-2) blockers that also includes ranitidine (Zantac), nizatidine (Axid), and famotidine …
Read More »Gardasil (HPV Vaccine): Drug Facts, Side Effects and Dosing
What is Gardasil Vaccine (HPV), and how does it work (mechanism of action)? Gardasil is a human papillomavirus (HPV) vaccine. Gardasil is a sterile preparation for intramuscular injection and contains purified inactive proteins from HPV types 6, 11, 16, and 18. The proteins in Gardasil are structural, virus-like proteins (VLP) that resemble the HPV virus. The proteins can activate the …
Read More »diclofenac, Voltaren, Cataflam, Cambia: Side Effects & Dosing
What is diclofenac, and how does it work (mechanism of action)? Diclofenac belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) that are used for the treatment of mild to moderate pain, fever, and inflammation. Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen (Aleve) and several others. NSAIDs work by reducing the production …
Read More »Ondansetron (Zofran): Anti-Nausea Drug Side Effects & Interactions
What is ondansetron oral disintegrating tablet, and how does it work (mechanism of action)? Ondansetron is an anti-nausea medication most often used to prevent nausea and vomiting caused by chemotherapy. Chemotherapy agents increase secretion of serotonin which stimulates serotonin (5-HT3) receptors in the brain, causing nausea and vomiting. Ondansetron works by selectively blocking serotonin (5-HT3) receptors, reducing the effect of …
Read More »telmisartan, Micardis: Drug Facts, Side Effects and Dosing
What is telmisartan, and how does it work (mechanism of action)? Telmisartan is a member of a family of drugs called angiotensin receptor blockers (ARBs), which includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand). Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in …
Read More »metoclopramide, Reglan: Drug Facts, Side Effects and Dosing
What is metoclopramide, and how does it work? Metoclopramide is a "prokinetic" drug that stimulates the muscles of the gastrointestinal tract including the muscles of the lower esophageal sphincter, stomach, and small intestine by interacting with receptors for acetylcholine and dopamine on gastrointestinal muscles and nerves. The lower esophageal sphincter, located between the esophagus and the stomach, normally prevents reflux …
Read More »Thyroid Replacement Hormones: Side Effects and Dosage
What are thyroid replacement hormones and how do they work? Thyroid replacement hormones are medications used to treat hypothyroidism, a condition in which the production of thyroid hormone in the body is abnormally low. Thyroid hormones increase cellular metabolism (activity of cells) that is responsible for growth, development of tissues, maintenance of brain function, body temperature regulation and several other …
Read More »SGLT2 Inhibitors
What are SGLT2 inhibitors? SGLT2 (sodium-glucose co-transporter 2) inhibitors are prescription oral medications used to treat type 2 diabetes. What generic and brand names of SGLT2 inhibitors are available in the US? Brand and generic names of SGLT2 inhibitors and combination products that contain SGLT2 inhibitors include: canagliflozin (Invokana) canagliflozin/metformin (Invokamet) canagliflozin/metformin extended release (Invokamet XR) dapagliflozin (Farxiga) dapagliflozin/metformin extended …
Read More »famciclovir, Famvir: Drug Facts, Side Effects and Dosing
What is famciclovir? What are the uses for famciclovir? Famciclovir is an antiviral drug which is active against the Herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes) and varicella-zoster (shingles and chickenpox). It belongs to a class of drugs called nucleoside analogs that mimic one of the building blocks of DNA. It stops the spread …
Read More »Lithium (Lithobid): Mood Stabilizing Medications, Side Effects & Dosage
What is lithium, and how does it work (mechanism of action)? Lithium is used for the treatment of manic/depressive (bipolar) and depressive disorders. Lithium is a positively charged element or particle that is similar to sodium and potassium. It interferes at several places inside cells and on the cell surface with other positively charged atoms such as sodium, potassium, calcium, …
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