Oral Cancer: Discover Facts about Cancer of the Mouth

Oral cancer facts*

*Oral cancer facts medical author: Charles P. Davis, MD, PhD

  • The oral cavity is complex and consists of lips, cheek lining, salivary glands, hard palate, soft palate, uvula, area under the tongue, gums, teach, tongue, and tonsils.
  • Oral cancer is abnormal (malignant) growth of body cells in any part of the oral cavity; oral cancer is sometimes termed head and neck cancer.
  • Risk factors for oral cancer are many; for example, tobacco use alcohol use, sun exposure (lips), anyone who has already had some form of head and neck cancer, and human papilloma virus infection.
  • Symptoms of oral cancer may include red, white and/or a mixture of these colors in patches, a non-healing sore in the mouth or on the lips, bleeding, loose teeth, swallowing problems, new denture problems, lumps or bumps on the neckm, and earaches.
  • Oral cancer is diagnosed by the patient’s history and physical exam and definitively by a biopsy of oral tissue; occasionally, CT scans, MRI scans or PET scans may be used.
  • The treatment of oral cancer is usually decided in conjunction with the patient’s doctor.
  • Methods of treatment for oral cancer include surgery, radiation therapy, and/or chemotherapy.
  • The side effects of oral cancer treatment may include pain, weakness, altered facial appearance, difficulty in swallowing or chewing food, dry mouth, tooth decay, sore throat, sore gums, bleeding, infections, denture problems, voice quality, thyroid problems, fatigue, hair loss, nausea, vomiting, and diarrhea.
  • Rehabilitation after oral cancer surgery consists of regaining strength, developing a healthy diet the patient can tolerate, and possibly dental implants or facial reconstruction surgery.
  • After treatment and rehabilitation (see above), checkups are needed to maintain health and make sure that the oral cancer does not recur.
  • Oral cancer treatment can result in significant lifestyle changes; most patients are advised to discuss lifestyle problems with professionals such as social workers to help patients get the care they may need.
  • This article provides several methods to discover what support groups are available to oral cancer patients.

Learn about prevention of oral cancer.

Oral Cancer Prevention

Oral cancer is sometimes associated with known risk factors for the disease.
Many risk factors can be modified but not all can be avoided.

  • Tobacco and alcohol use:
    Tobacco use (cigarettes, pipes, cigars, and smokeless tobacco) is
    responsible for most cases of oral cancer. Alcohol, particularly beer and
    hard liquor, are associated with an increased risk of developing oral
    cancer. The risk of developing oral cancer is higher in people who use both
    tobacco and alcohol. Avoiding or stopping the use of tobacco decreases the
    risk of oral cancer. It is not known if stopping the use of alcohol
    decreases the risk of oral cancer.
  • Sun exposure: Exposure to sunlight may increase the risk of lip cancer,
    which occurs most often on the lower lip. Avoiding the sun and/or using a
    sunscreenor colored lipstick on the lips may decrease the risk of lip
  • Other factors: Some studies suggest that being infected with the human
    papillomavirus (HPV) may increase the risk of oral cancer.
  • Chemoprevention: Chemopreventionis the use of drugs, vitamins, or other
    agents to prevent or delay the growth of cancer or to keep it from coming
    back. Tobacco users who have had oral cancer often develop second cancers in
    the oral cavity or nearby areas, including the nose, throat, vocal cords,
    esophagus, and windpipe. Studies of chemoprevention in oral cancer are under
    way, including chemoprevention of leukoplakia and erythroplakia.

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    What are the symptoms of oral cancer?

    Early detection

    Your regular checkup is a good time for your dentist or doctor to check your entire mouth for signs of cancer. Regular checkups can detect the early stages of oral cancer or conditions that may lead to oral cancer. Ask your doctor or dentist about checking the tissues in your mouth as part of your routine exam.


    Common symptoms of oral cancer include:

    • Patches inside your mouth or on your lips that are white, a mixture of red and white, or red
      • White patches (leukoplakia) are the most common. White patches sometimes become malignant.
      • Mixed red and white patches (erythroleukoplakia) are more likely than white patches to become malignant.
      • Red patches (erythroplakia) are brightly colored, smooth areas that often become malignant.
    • A sore on your lip or in your mouth that won’t heal
    • Bleeding in your mouth
    • Loose teeth
    • Difficulty or pain when swallowing
    • Difficulty wearing dentures
    • A lump in your neck
    • An earache

    Anyone with these symptoms should see a doctor or dentist so that any problem can be diagnosed and treated as early as possible. Most often, these symptoms do not mean cancer. An infection or another problem can cause the same symptoms.


    What causes tooth decay?
    See Answer

    How is oral cancer diagnosed?

    If you have symptoms that suggest oral cancer, the doctor or dentist checks your mouth and throat for red or white patches, lumps, swelling, or other problems. This exam includes looking carefully at the roof of the mouth, back of the throat, and insides of the cheeks and lips. The doctor or dentist also gently pulls out your tongue so it can be checked on the sides and underneath. The floor of your mouth and lymph nodes in your neck also are checked.

    If an exam shows an abnormal area, a small sample of tissue may be removed. Removing tissue to look for cancer cells is called a biopsy. Usually, a biopsy is done with local anesthesia. Sometimes, it is done under general anesthesia. A pathologist then looks at the tissue under a microscope to check for cancer cells. A biopsy is the only sure way to know if the abnormal area is cancerous.

    If you need a biopsy, you may want to ask the doctor or dentist some of the following questions:

    • Why do I need a biopsy?
    • How much tissue do you expect to remove?
    • How long will it take? Will I be awake? Will it hurt?
    • How soon will I know the results?
    • Are there any risks? What are the chances of infection or bleeding after the biopsy?
    • How should I care for the biopsy site afterward? How long will it take to heal?
    • Will I be able to eat and drink normally after the biopsy?
    • If I do have cancer, who will talk with me about treatment? When?

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    How is oral cancer treated?


    If the biopsy shows that cancer is present, your doctor needs to know the stage (extent) of your disease to plan the best treatment. The stage is based on the size of the tumor, whether the cancer has spread and, if so, to what parts of the body.

    Staging may require lab tests. It also may involve endoscopy. The doctor uses a thin, lighted tube (endoscope) to check your throat, windpipe, and lungs.
    The endoscope may be flexible or rigid. The doctor inserts the endoscope through your nose or mouth. Local anesthesia is used to ease your discomfort and prevent you from gagging. Some people also may have a mild sedative. Sometimes the doctor uses general anesthesia to put a person to sleep. This exam may be done in a doctor’s office, an outpatient clinic, or a hospital.

    The doctor may order one or more imaging tests to learn whether the cancer has spread:

    • Dental x-rays: An x-ray of your entire mouth can show whether cancer has spread to the jaw.
    • Chest x-rays: Images of your chest and lungs can show whether cancer has spread to these areas.
    • CT scan: An x-ray machine linked to a computer takes a series of detailed pictures of your body. You may receive an injection of dye. Tumors in the mouth, throat, neck, or elsewhere in the body show up on the CT scan.
    • MRI: A powerful magnet linked to a computer is used to make detailed pictures of your body. The doctor can view these pictures on a monitor and can print them on film. An MRI can show whether oral cancer has spread.
    • PET scan: A small amount of radioactive sugar is given into the vein. Cancer cells use sugar differently than normal cells. A scan for radioactivity may then help to localize cancer cells. The PET scan is often done along with a CT scan.


    Many people with oral cancer want to take an active part in making decisions about their medical care. It is natural to want to learn all you can about your disease and your treatment choices. However, shock and stress after the diagnosis can make it hard to think of everything you want to ask the doctor. It often helps to make a list of questions before an appointment. To help remember what the doctor says, you may take notes or ask whether you may use a tape recorder. You may also want to have a family member or friend with you when you talk to the doctor – to take part in the discussion, to take notes, or just to listen.

    Your doctor may refer you to a specialist, or you may ask for a referral. Specialists who treat oral cancer include oral and maxillofacial surgeons, otolaryngologists (ear, nose, and throat doctors), medical oncologists, radiation oncologists, and plastic surgeons. You may be referred to a team that includes specialists in surgery, radiation therapy, or chemotherapy. Other health care professionals who may work with the specialists as a team include a dentist, speech pathologist, nutritionist, and mental health counselor.

    Getting a second opinion

    Before starting treatment, you might want a second opinion about the diagnosis and the treatment plan. Some insurance companies require a second opinion; others may cover a second opinion if you or your doctor requests it. Do not be afraid to ask for a second opinion. These are serious conditions and you may want to learn about your diagnosis and treatment options from more than one source. Your doctor should not be offended if you ask for a second opinion, and can help you to arrange it, if asked.

    There are a number of ways to find a doctor for a second opinion:

    • Your doctor may refer you to one or more specialists. At cancer centers, several specialists often work together as a team.
    • The Cancer Information Service, at 1-800-4-CANCER, can tell you about nearby treatment centers.
    • A local or state medical or dental society, a nearby hospital, or a medical or dental school can usually provide the names of specialists in your area.
    • The American Board of Medical Specialties (ABMS) has a list of doctors who have had training and exams in their specialty. You can find this list in the Official ABMS Directory of Board Certified Medical Specialists. The directory is available in most public libraries. Or you can look up doctors at http://www.abms.org. (Click on Who’s Certified.)
    • The American Dental Association (ADA) Web site provides a list of dentists by specialty and location. The ADA Member Directory is available on the Internet at http://www.ada.org.
    • The NCI provides a helpful fact sheet on how to find a doctor called “How To Find a Doctor or Treatment Facility If You Have Cancer.” It is available on the Internet at http://cancer.gov/publications.

    You may want to ask the doctor these questions before treatment begins:

    • What is the stage of the disease? Has the cancer spread? If so, where?
    • What are my treatment choices? Which do you recommend for me? Will I have more than one kind of treatment?
    • What are the expected benefits of each kind of treatment?
    • What are the risks and possible side effects of each treatment? How will treatment affect my normal activities? Will I be given anything to control side effects?
    • How long will treatment last?
    • Will I have to stay in the hospital?
    • What is the treatment likely to cost? Is this treatment covered by my insurance plan?
    • Would a clinical trial (research study) be appropriate for me? (See “The Promise of Cancer Research” for more information about clinical trials.)
    • Should I try to quit smoking?

    Preparing for treatment

    The choice of treatment depends mainly on your general health, where in your mouth or oropharynx the cancer began, the size of the tumor, and whether the cancer has spread. Your doctor can describe your treatment choices and the expected results. You will want to consider how treatment may affect normal activities such as swallowing and talking, and whether it will change the way you look. You and your doctor can work together to develop a treatment plan that meets your needs and personal values.

    You do not need to ask all your questions or understand all the answers at once. You will have other chances to ask your doctor to explain things that are not clear and to ask for more information.

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    Methods of treatment

    Oral cancer treatment may include surgery, radiation therapy, or chemotherapy. Some patients have a combination of treatments.

    At any stage of disease, people with oral cancer may have treatment to control pain and other symptoms, to relieve the side effects of therapy, and to ease emotional and practical problems. This kind of treatment is called supportive care, symptom management, or palliative care. Information about supportive care is available on NCI’s Web site at http://cancer.gov and from NCI’s Cancer Information Service at 1-800-4-CANCER.

    You may want to talk to the doctor about taking part in a clinical trial, a research study of new treatment methods. The section on “The Promise of Cancer Research” has more information about clinical trials.


    Surgery to remove the tumor in the mouth or throat is a common treatment for oral cancer. Sometimes the surgeon also removes lymph nodes in the neck. Other tissues in the mouth and neck may be removed as well. Patients may have surgery alone or in combination with radiation therapy.

    You may want to ask the doctor these questions before having surgery:

    • What kind of operation do you recommend for me?
    • Do I need any lymph nodes removed? Why?
    • How will I feel after the operation? How long will I be in the hospital?
    • What are the risks of surgery?
    • Will I have trouble speaking, swallowing, or eating?
    • Where will the scars be? What will they look like?
    • Will I have any long-term effects?
    • Will I look different?
    • Will I need reconstructive or plastic surgery? When can that be done?
    • Will I lose my teeth? Can they be replaced? How soon?
    • Will I need to see a specialist for help with my speech?
    • When can I get back to my normal activities?
    • How often will I need checkups?
    • Would a clinical trial be appropriate for me?

    Radiation therapy

    Radiation therapy (also called radiotherapy) is a type of local therapy. It affects cells only in the treated area. Radiation therapy is used alone for small tumors or for patients who cannot have surgery. It may be used before surgery to kill cancer cells and shrink the tumor. It also may be used after surgery to destroy cancer cells that may remain in the area.

    Radiation therapy uses high-energy rays to kill cancer cells. Doctors use two types of radiation therapy to treat oral cancer:

    • External radiation: The radiation comes from a machine. Patients go to the hospital or clinic once or twice a day, generally 5 days a week for several weeks.
    • Internal radiation (implant radiation): The radiation comes from radioactive material placed in seeds, needles, or thin plastic tubes put directly in the tissue. The patient stays in the hospital. The implants remain in place for several days. Usually they are removed before the patient goes home.

    Some people with oral cancer have both kinds of radiation therapy.

    You may want to ask the doctor these questions before having radiation therapy:

    • Which type of radiation therapy do you recommend for me? Why do I need this treatment?
    • When will the treatments begin? When will they end?
    • Should I see my dentist before I start treatment? If I need dental treatment, how much time does my mouth need to heal before radiation therapy starts?
    • What are the risks and side effects of this treatment? What can I do about them?
    • How will I feel during therapy?
    • What can I do to take care of myself during therapy?
    • How will my mouth and face look afterward?
    • Are there any long-term effects?
    • Can I continue my normal activities?
    • Will I need a special diet? For how long?
    • How often will I need checkups?
    • Would a clinical trial be appropriate for me?


    Chemotherapy uses anticancer drugs to kill cancer cells. It is called systemic therapy because it enters the bloodstream and can affect cancer cells throughout the body.
    A new targeted therapy called cetuximab, which blocks a growth factor upon which
    cancer cells may depend, is being used today, either alone or in combination
    with radiation and older chemotherapy drugs.

    Chemotherapy is usually given by injection. It may be given in an outpatient part of the hospital, at the doctor’s office, or at home. Rarely, a hospital stay may be needed.

    You may want to ask the doctor these questions before having chemotherapy:

    • Why do I need this treatment?
    • Which drug or drugs will I have?
    • How do the drugs work?
    • Should I see my dentist before I start chemotherapy? If I need dental treatment, how much time does my mouth need to heal before the chemotherapy begins?
    • What are the expected benefits of the treatment?
    • What are the risks and possible side effects of treatment? What can I do about them?
    • When will treatment start? When will it end?
    • Will I need to stay in the hospital? How long?
    • How will treatment affect my normal activities?
    • Would a clinical trial be appropriate for me?


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    What are the side effects of treatment for oral cancer?

    Because treatment often damages healthy cells and tissues, unwanted side effects are common. These side effects depend mainly on the location of the tumor and the type and extent of the treatment. Side effects may not be the same for each person, and they may even change from one treatment session to the next. Before treatment starts, your health care team will explain possible side effects and suggest ways to help you manage them.

    The NCI provides helpful booklets about cancer treatments and coping with side effects. Booklets such as Radiation Therapy and You, Chemotherapy and You, and Eating Hints for Cancer Patients may be viewed, downloaded, and ordered from http://cancer.gov/publications. These materials also may be ordered by calling the Cancer Information Service at 1-800-4-CANCER.

    The National Institute of Dental and Craniofacial Research (NIDCR) also provides helpful materials. Head and Neck Radiation Treatment and Your Mouth, Chemotherapy and Your Mouth, and other booklets are available from NIDCR. See “National Institute of Dental and Craniofacial Research Information Resources” for a list of publications.


    It takes time to heal after surgery, and the time needed to recover is different for each person. You may be uncomfortable for the first few days after surgery. However, medicine can usually control the pain. Before surgery, you should discuss the plan for pain relief with your doctor or nurse. After surgery, your doctor can adjust the plan if you need more pain relief.

    It is common to feel tired or weak for a while. Also, surgery may cause tissues in your face to swell. This swelling usually goes away within a few weeks. However, removing lymph nodes can result in swelling that lasts a long time.

    Surgery to remove a small tumor in the mouth may not cause any lasting problems. For a larger tumor, however, the surgeon may remove part of the palate, tongue, or jaw. This surgery may change your ability to chew, swallow, or talk. Also, your face may look different after surgery. Reconstructive or plastic surgery may be done to rebuild the bones or tissues of the mouth. (See “Reconstruction.”)

    Radiation therapy

    Almost all patients who have radiation therapy to the head and neck area develop oral side effects. That is why it is important to get the mouth in good condition before cancer treatment begins. Seeing a dentist two weeks before cancer treatment begins gives the mouth time to heal after dental work.

    The side effects of radiation therapy depend mainly on the amount of radiation given. Some side effects in the mouth go away after radiation treatment ends, while others last a long time. A few side effects (such as dry mouth) may never go away.

    Radiation therapy may cause some or all of these side effects:

    • Dry mouth: Dry mouth can make it hard for you to eat, talk, and swallow. It can also lead to tooth decay. You may find it helpful to drink lots of water, suck ice chips or sugar-free hard candy, and use a saliva substitute to moisten your mouth.
      This problem can be permanent or temporary.
    • Tooth decay: Radiation can cause major tooth decay problems. Good mouth care can help you keep your teeth and gums healthy and can help you feel better.
      • Doctors usually suggest that people gently brush their teeth, gums, and tongue with an extra-soft toothbrush and fluoride toothpaste after every meal and before bed. If brushing hurts, you can soften the bristles in warm water.
      • Your dentist may suggest that you use fluoride gel before, during, and after radiation treatment.
      • It also helps to rinse your mouth several times a day with a solution made from 1/4 teaspoon baking soda and 1/8 teaspoon salt in one cup of warm water. After you rinse with this solution, follow with a plain water rinse.
    • Sore throat or mouth: Radiation therapy can cause painful ulcers and inflammation. Your doctor can suggest medicines to help control the pain. Your doctor also may suggest special rinses to numb the throat and mouth to help relieve the soreness. If your pain continues, you can ask your doctor about stronger medicines.
    • Sore or bleeding gums: It is important to brush and floss teeth gently. You may want to avoid areas that are sore or bleeding. To protect your gums from damage, it is a good idea to avoid the use of toothpicks.
    • Infection: Dry mouth and damage to the lining of the mouth from radiation therapy can cause infection to develop. It helps to check your mouth every day for sores or other changes and to tell your doctor or nurse about any mouth problems.
    • Delayed healing after dental care: Radiation treatment may make it hard for tissues in the mouth to heal. It helps to have a thorough dental exam and complete all needed dental treatment well before radiation therapy begins.
    • Jaw stiffness: Radiation can affect the chewing muscles and make it difficult for you to open your mouth. You can prevent or reduce jaw stiffness by exercising your jaw muscles. Health care providers often suggest opening and closing the mouth as far as possible (without causing pain) 20 times in a row, 3 times a day.
    • Denture problems: Radiation therapy can change the tissues in your mouth so that dentures do not fit anymore. Because of soreness and dry mouth, some people may not be able to wear dentures for as long as one year after radiation therapy. After the tissues heal completely and your mouth is no longer sore, your dentist may need to refit or replace your dentures.
    • Changes in the sense of taste and smell: During radiation therapy, food may taste or smell different.
    • Changes in voice quality: Your voice may be weak at the end of the day. It may also be affected by changes in the weather. Radiation directed at the neck may cause your larynx to swell, causing voice changes and the feeling of a lump in your throat. Your doctor may suggest medicine to reduce this swelling.
    • Changes in the thyroid: Radiation treatment can affect your thyroid (an organ in your neck beneath the voice box). If your thyroid does not make enough thyroid hormone, you may feel tired, gain weight, feel cold, and have dry skin and hair. Your doctor can check the level of thyroid hormone with a blood test. If the level is low, you may need to take thyroid hormone pills.
    • Skin changes in the treated area: The skin in the treated area may become red or dry. Good skin care is important at this time. It is helpful to expose this area to the air while protecting it from the sun. Also, avoid wearing clothes that rub the treated area, and do not shave the treated area. You should not use lotions or creams in the treated area without your doctor’s advice.
    • Fatigue: You may become very tired, especially in the later weeks of radiation therapy. Resting is important, but doctors usually advise their patients to stay as active as they can.

    Although the side effects of radiation therapy can be distressing, your doctor can usually treat or control them. It helps to report any problems that you are having so that your doctor can work with you to relieve them.


    Chemotherapy and radiation therapy can cause some of the same side effects, including
    skin rashes, painful mouth and gums, dry mouth, infection, and changes in taste. Some anticancer drugs can also cause bleeding in the mouth and a deep pain
    in the jaw that feels like a toothache. The problems you have depend on the type and amount of anticancer drugs you receive, and how your body reacts to them. You may have these problems only during treatment or for a short time after treatment ends.

    Generally, anticancer drugs affect cells that divide rapidly. In addition to cancer cells, these rapidly dividing cells include the following:

    • Blood cells: These cells fight infection, help your blood to clot, and carry oxygen to all parts of the body. When drugs affect your blood cells, you are more likely to get infections, bruise or bleed easily, and feel very weak and tired.
    • Cells in hair roots: Chemotherapy can lead to hair loss. The hair grows back, but sometimes the new hair is somewhat different in color and texture.
    • Cells that line the digestive tract: Chemotherapy can cause poor appetite, nausea and vomiting, diarrhea, or mouth and lip sores. Many of these side effects can be controlled with drugs.

    What is rehabilitation for oral cancer?

    Eating well during cancer treatment means getting enough calories and protein to prevent weight loss, regain strength, and rebuild healthy tissues. But eating well may be difficult after treatment for oral cancer. Some people with cancer find it hard to eat because they lose their appetite. They may not feel like eating because they are uncomfortable or tired. A dry or sore mouth or changes in smell and taste also may make eating difficult.

    If your mouth is dry, you may find that soft foods moistened with sauces or gravies are easier to eat. Thick soups, puddings, and milkshakes often are easier to swallow. Nurses and dietitians can help you choose the right foods. Also, the National Cancer Institute booklet Eating Hints for Cancer Patients contains many useful ideas and recipes. The “National Cancer Institute Information Resources” section tells how to get this publication.

    After surgery or radiation therapy for oral cancer, some people need a feeding tube. A feeding tube is a flexible plastic tube that is passed into the stomach through an incision in the abdomen. In almost all cases, the tube is temporary. Most people gradually return to a regular diet.

    To protect your mouth during cancer treatment, it helps to avoid:

    • Sharp, crunchy foods like taco chips
    • Foods that are hot, spicy, or high in acid like citrus fruits and juices
    • Sugary foods that can cause cavities
    • Alcoholic drinks


    Some people with oral cancer may need to have plastic or reconstructive surgery to rebuild the bones or tissues of the mouth. Research has led to many advances in the way bones and tissues can be replaced.

    Some people may need dental implants. Or they may need to have grafts (tissue moved from another part of the body). Skin, muscle, and bone can be moved to the oral cavity from the chest, arm, or leg. The plastic surgeon uses this tissue for repair.

    If you are thinking about reconstruction, you may wish to consult with a plastic or reconstructive surgeon before your treatment begins. You can have reconstructive surgery at the same time as you have the cancer removed, or you can have it later on. Talk with your doctor about which approach is right for you.


    The health care team will help you return to normal activities as soon as possible. The goals of rehabilitation depend on the extent of the disease and type of treatment. Rehabilitation may include being fitted with a dental prosthesis (an artificial dental device) and having dental implants. It also may involve speech therapy, dietary counseling, or other services.

    Sometimes surgery to rebuild the bones or tissues of the mouth is not possible. A dentist with special training (a prosthodontist) may be able to make you a prosthesis to help you eat and talk normally. You may need special training to learn to use it.

    If oral cancer or its treatment leads to problems with talking, speech therapy will generally begin as soon as possible. A speech therapist may see you in the hospital to plan therapy and teach speech exercises. Often speech therapy continues after you return home.

    What happens after treatment for oral cancer?

    Follow-up care after treatment for oral cancer is important. Even when the cancer seems to have been completely removed or destroyed, the disease sometimes returns because undetected cancer cells remained in the body after treatment. The doctor monitors your recovery and checks for recurrence of cancer. Checkups help ensure that any changes in your health are noted. Your doctor will probably encourage you to inspect your mouth regularly and continue to have exams when you visit your dentist. It is important to report any changes in your mouth right away.

    Checkups include exams of the mouth, throat, and neck. From time to time, your doctor may do a complete physical exam, order blood tests, and take x-rays.

    People who have had oral cancer have a chance of developing a new cancer in the mouth, throat, or other areas of the head and neck. This is especially true for those who use tobacco or who drink alcohol heavily. Doctors strongly urge their patients to
    STOP using tobacco and drinking to cut down the risk of a new cancer and other health problems.

    The NCI has prepared a booklet for people who have completed their treatment to help answer questions about follow-up care and other concerns. Facing Forward Series: Life After Cancer Treatment provides tips for making the best use of medical visits. It describes how to talk to your health care team about creating a plan of action for recovery and future health.

    What does the future hold for patients with oral cancer?

    Living with a serious disease such as oral cancer is not easy. You may worry about caring for your family, keeping your job, or continuing daily activities. You may have concerns about treatments and managing side effects, hospital stays, and medical bills. Doctors, nurses, and other members of the health care team can answer your questions about treatment, working, or other activities. Meeting with a social worker, counselor, or member of the clergy can be helpful if you want to talk about your feelings or discuss your concerns. Often, a social worker can suggest resources for financial aid, transportation, home care, or emotional support.

    Support groups also can help. In these groups, patients or their family members meet with other patients or their families to share what they have learned about coping with the disease and the effects of treatment. Groups may offer support in person, over the telephone, or on the Internet. You may want to talk with a member of your health care team about finding a support group. The NCI’s fact sheets “Cancer Support Groups: Questions and Answers” and “National Organizations That Offer Services to People With Cancer and Their Families” tell how to find a support group. See “National Cancer Institute Information Resources” for ordering information.

    The Cancer Information Service can provide information to help patients and their families locate programs, services, and publications.

    The promise of cancer research

    Doctors all over the country are conducting many types of clinical trials. These are research studies in which people volunteer to take part. In clinical trials, doctors are testing new ways to treat oral cancer. Research has already led to advances, and researchers continue to search for more effective approaches.

    People who join clinical trials may be among the first to benefit if a new approach is shown to be effective. And if participants do not benefit directly, they still make an important contribution to medical science by helping doctors learn more about the disease and how to control it. Although clinical trials may pose some risks, researchers do all they can to protect their patients.

    Researchers are testing anticancer drugs and combinations of drugs. They are studying radiation therapy combined with drugs and other treatments. They also are testing drugs that prevent or reduce the side effects of radiation therapy.

    If you are interested in learning more about joining a clinical trial, you may want to talk with your doctor. You may want to read Taking Part in Clinical Trials: What Cancer Patients Need To Know. The NCI also offers an easy-to-read brochure called If You Have Cancer…What You Should Know About Clinical Trials. These NCI publications describe how research studies are carried out and explain their possible benefits and risks.

    NCI’s Web site includes a section on clinical trials at http://cancer.gov/clinicaltrials with general information about clinical trials and detailed information about specific studies. The Cancer Information Service at 1-800-4-CANCER or at LiveHelp at http://cancer.gov can answer questions and provide information about clinical trials. Another source of information about clinical trials is http://clinicaltrials.gov.

    What resources are available to patients with oral cancer?

    You may want more information for yourself, your family, and your doctor. The following National Cancer Institute (NCI) services are available to help you.

    TelephoneCancer Information Service (CIS) Provides accurate, up-to-date information on cancer to patients and their families, health professionals, and the general public. Information Specialists translate the latest scientific information into understandable language and respond in English, Spanish, or on TTY equipment.

    Toll-free: 1-800-4-CANCER (1-800-422-6237) TTY: 1-800-332-8615

    Internethttp://cancer.gov The NCI’s Cancer.gov™ Web site provides information from numerous NCI sources. It offers current information on cancer prevention, screening, diagnosis, treatment, genetics, supportive care, and ongoing clinical trials. It also provides information about NCI’s research programs and funding opportunities, cancer statistics, and the Institute itself. Cancer.gov provides live, online assistance through LiveHelp. Cancer.gov is at http://cancer.gov on the Internet.

    http://www.smokefree.gov The Tobacco Control Research Branch of NCI, in collaboration with the Centers for Disease Control and Prevention and the American Cancer Society, created a smoking cessation Web site. It offers online quitting advice through NCI’s LiveHelp service. It also provides national and state telephone quitline numbers and access to printed materials about quitting tobacco. It is located on the Internet at http://www.smokefree.gov.

    Print materialsYou can order National Cancer Institute (NCI) publications by writing to the address below:

    Publications Ordering Service
    National Cancer Institute
    Suite 3036A
    Executive Boulevard, MSC 8322
    Bethesda, MD 20892-8322

    Some NCI publications can be viewed, downloaded, and ordered from http://cancer.gov/publications on the Internet. If you are in the United States or one of its territories, you may order these and other NCI booklets by calling the Cancer Information Service at 1-800-4-CANCER.

    National Institute of Dental and Craniofacial Research information resources

    The National Oral Health Information ClearinghouseThis Clearinghouse is a service of the Federal Government’s National Institute of Dental and Craniofacial Research (NIDCR). NIDCR’s mission is to promote the general health of the American people by improving their oral, dental, and craniofacial health. Through the conduct and support of research and the training of researchers, the NIDCR aims to promote health, prevent diseases and conditions, and develop new diagnostics and therapies.

    NIDCR directs the health awareness campaign, Oral Health, Cancer Care, and You: Fitting the Pieces Together. The campaign addresses the importance of preventing and managing the oral side effects of cancer treatments. It is a partnership among NIDCR, NCI, National Institute of Nursing Research, and Centers for Disease Control and Prevention.

    NIDCR can supply free information about oral cancer and taking care of your mouth during cancer treatment. Booklets are available in English and Spanish:

    • Chemotherapy and Your Mouth
    • Head and Neck Radiation Treatment and Your Mouth
    • Quimioterapia y la Boca (Chemotherapy and Your Mouth)
    • Su Boca y el Tratamiento de Radiación en la Cabeza y el Cuello (Head and Neck Radiation and Your Mouth)

    Materials may be obtained by contacting the Clearinghouse:
    National Institute
    of Dental and Craniofacial Research
    National Oral Health Information
    Attn: OCCT
    1 NOHIC Way
    Bethesda, MD 20892-3500
    Tel: 301-402-7364

    Materials are also available online at http://www.nidcr.nih.gov under “health information.”

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