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Tradjenta (linagliptin): Diabetes Drug Side Effects & Dosage

What is linagliptin? What are the uses for linagliptin?

  • Tradjenta is combined with
    diet and
    exercise to improve
    blood glucose levels in patients with
    type 2 diabetes.
  • It should not be used for treating type 1 diabetes or
    diabetic ketoacidosis because it would not be effective in these conditions.
  • Tradjenta has not been studied in patients with a history of
    pancreatitis. It is unknown whether
    Tradjenta increases the risk for the
    development of pancreatitis in patients who have a history of pancreatitis.

What brand names are available for linagliptin?

Tradjenta

Is linagliptin available as a generic drug?

No

Do I need a prescription for linagliptin?

Yes

What are the side effects of linagliptin?

The most common side effects of Tradjenta are:

Hypoglycemia
may occur when Tradjenta is combined with insulin or a sulfonylurea-type drug.

Possible serious side effects include:

  • Pancreatitis
  • Severe joint pain
  • Severe allergic reactions (anaphalaxis)

What is the dosage for linagliptin?

Tradjenta may be taken with or without food. The recommended dose
is 5 mg once daily.

Which drugs or supplements interact with linagliptin?

  • Rifampin decreases the blood concentration of Tradjenta
    by stimulating break down of Tradjenta by CYP3A4
    liver enzymes. Other
    drugs
    that increase activity CYP3A4 may also reduce the blood concentration of
    Tradjenta.

Is linagliptin safe to take if I’m pregnant or breastfeeding?

  • There are no adequate studies of Tradjenta in pregnant women.
  • It is unknown whether Tradjenta is secreted in human
    breast milk.

What else should I know about linagliptin?

What preparations of linagliptin are available?

Tablets: 5 mg

How should I keep linagliptin stored?

Tablets should be stored at room temperature, 15-30 C (59-86 F)

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