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clomiphene (Clomid): Fertility Drug Side Effects & Dosage

What is clomiphene, and how does it work (mechanism of action)?

Clomiphene is an oral medication used for stimulating ovulation. It binds to estrogen receptors in the hypothalamus, pituitary gland, ovary, endometrium, vagina, and cervix. It causes production of hormones (gonadotropins) by the pituitary which stimulates ovulation. The FDA approved clomiphene in February 1967.

What brand names are available for clomiphene?


Is clomiphene available as a generic drug?


Do I need a prescription for clomiphene?


What are the side effects of clomiphene?

The most common side effects of clomiphene are:

Other important side effects include


Men and women are equally likely to have fertility problems.
See Answer

What is the dosage for clomiphene?

The recommended dose is 50 to 100 mg orally for 5 days. The initial dose is 50 mg which may be increased to 100 mg if there is no response. Dosage may be repeated as early as 30 days after the previous treatment.

Which drugs or supplements interact with clomiphene?

No drug interactions are listed in the prescribing information.

Is clomiphene safe to take if I’m pregnant or breastfeeding?

Clomiphene should not be taken by pregnant women since it does not offer any benefit to
pregnant women.

It is not known whether clomiphene is excreted into
breast milk. It may reduce lactation in some women.

What else should I know about clomiphene?

What preparations of clomiphene are available?

Tablets: 50 mg

How should I keep clomiphene stored?

Tablets should be stored at room temperature, 15 C to 30 C (59 F to 86 F).


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