What are proton pump inhibitors (PPIs), and how do they work (mechanism of action)? Proton pump inhibitors (PPIs) reduce the production of acid by blocking the enzyme in the wall of the stomach that produces acid. Acid is necessary for the formation of most ulcers in the esophagus, stomach, and duodenum, and the reduction of …
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What is levofloxacin? How does it work (mechanism of action)? Levofloxacin is an antibiotic that is used for treating bacterial infections. Many common infections in humans are caused by bacteria. Bacteria can grow and multiply, infecting different parts of the body. Drugs that control and eradicate these bacteria are called antibiotics. Levofloxacin is an antibiotic that stops multiplication of bacteria …
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What is nitrofurantoin (Macrobid, Macrodantin, Furadantin)? Nitrofurantoin is an antibiotic that is used for treating urinary tract infections caused by several types of bacteria. It is effective against E. Coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus. Nitrofurantoin interferes with the production of bacterial proteins, DNA, and cell walls. Bacteria cannot survive without a cell wall or multiply without DNA. …
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What is topical metronidazole? How does it work (mechanism of action)? Metronidazole is a synthetic (man-made) drug that is effective against certain bacteria and parasites (protozoa). The topical forms (gels, creams, and lotions) of metronidazole are used for treating vaginal infections with protozoa such as Trichomonas vaginalis, amoeba, and Giardia. Metronidazole topical also is effective against anaerobic bacterial infections. (Anaerobic …
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What is Zepatier, and how does it work? Zepatier is an oral tablet containing two drugs used for the treatment of chronic infection with the hepatitis C virus (HCV), genotype 1 and 4 in adults. The components belong to a class of drugs called direct-acting antiviral agents. Similar drugs include: boceprevir (Victrelis) sofosbuvir (Sovaldi) simeprevir (Olysio) telaprevir (Incivek), Viekira Pak …
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What is methoxsalen? How does it work (mechanism of action)? Methoxsalen is a naturally occurring photoactive chemical found in the seeds of the Ammi majus (Umbelliferae) plant and in the roots of Heraclem candicans. It belongs to a group of compounds known as psoralens, or furocoumarins. It is used for treating psoriasis, idiopathic vitiligo (leucoderma) and cutaneous (skin) manifestations of …
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What is zidovudine? How does it work (mechanism of action)? Zidovudine (formerly called azidothymidine [AZT]), a pyrimidine nucleoside analogue active against HIV. RETROVIR IV Infusion is a sterile solutionfor intravenous infusion only. Each mL contains 10 mg zidovudine in Water for Injection. Hydrochloric acid and/or sodium hydroxide may have been added to adjust the pH to approximately 5.5. RETROVIR IV Infusion contains …
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What is pramoxine-hydrocortisone lotion? How does it work (mechanism of action)? Pramoxine-hydrocortisone products are used to treat pain and inflammation caused by various skin conditions. Hydrocortisone is a synthetic (man-made) corticosteroid that is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune …
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What is saquinavir? How does it work (mechanism of action)? Saquinavir is an oral medication that is used for treating infections with the human immunodeficiency virus (HIV). It is in a class of drugs called protease inhibitors which also includes indinavir (Crixivan), nelfinavir (Viracept) and ritonavir (Norvir). During infection with HIV, the HIV virus multiplies within the body's cells. Viruses …
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What is popcorn lung (bronchiolitis obliterans)? Readers Comments 2 Share Your Story Popcorn lung is a serious and irreversible condition in which the tiny air sacs in the lungs become scarred and constricted, which results in no air movement or O2 – CO2 exchange in the lungs. Other names for popcorn lung are bronchiolitis obliterans and obliterative bronchiolitis. Can e-cigarettes …
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