Caffeine Pills (Enerjets, No Doz, Vivarin): Side Effects & Dosage

What are oral caffeine tablets, and how do they work (mechanism of action)?

Caffeine acts as a stimulant of the nervous system by inhibiting the enzyme phosphodiesterase, just like theophylline and aminophylline. Inhibiting this enzyme leads to increased formation of the proteins which causes release of stimulating chemical signals known as neurotransmitters. These neurotransmitters bind to various sites in the body, including the brain, heart, and muscles to cause a stimulant effect.

What brand names are available for oral caffeine tablets?

Enerjets, No Doz, Vivarin

Are oral caffeine tablets available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for oral caffeine tablets?

No

What are the uses for oral caffeine tablets?

Caffeine (Enerjets, No Doz, Vivarin) is an over-the-counter (OTC) stimulant used to revive mental alertness and wakefulness when feeling fatigue and drowsiness or experiencing caffeine withdrawal.

What are the side effects of oral caffeine tablets?

Side effects associated with caffeine supplements include irregular heartbeat, chest pain, flushing, palpitations, rapid heartbeat, agitation, dizziness, hallucinations, headache, insomnia, irritability, psychosis, restlessness, rash, increased pressure in the eye, and frequent urination.

What is the dosage for oral caffeine tablets?

100 to 200 mg every 3 to 4 hours as needed no later than 6 hours before bedtime.

Which drugs or supplements interact with oral caffeine tablets?

Combining caffeine with other stimulating agents, such as methylphenidate (Ritalin, Ritalin SR, Ritalin LA, Concerta, Methylin, Methylin ER, Metadate CD, Metadate ER), should be done with caution. This combination may cause increased side effects including rapid heartbeat, high blood pressure, hallucinations, tremor, and anxiety. Other dietary sources of caffeine, such as tea, add to the effect. Caffeine should be used with caution with adenosine, as the effects of adenosine may be diminished. Linezolid, phenelzine, selegiline, and tranylcypromine combined with caffeine increases the risk of high blood pressure. Consider alternatives when combining caffeine and vemurafenib and Stiripentol as caffeine concentrations may be increased.

Are oral caffeine tablets safe to take if I’m pregnant or breastfeeding?

Category C; usual dietary exposure to caffeine is unlikely to cause congenital malformations, however studies show conflicting results about adverse events. Concentrations in the mother are similar to those found in the fetus. Daily intake should be no more than 200 mg.

Caffeine enters the breast milk, and, therefore should be used cautiously by nursing mothers.

What else should I know about oral caffeine tablets?

What preparations of oral caffeine tablets are available?

Tablets: 200 mg; Lozenge: 75mg

How should I keep oral caffeine tablets stored?

Caffeine should be stored at room temperature, between 20 C to 25 C (68 F to 77 F).

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