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Azelaic Acid (Finacea, Azelex) Side Effects, Uses & Dosage

What is azelaic acid gel, and how does it work (mechanism of action)?

  • Azelaic acid is a topical (applied to the skin) medication used for treating
    acne. Its exact mechanism of action is unknown. Azelaic acid may work as an
    antibacterial agent that blocks protein synthesis and therefore growth of
    Propionibacterium acnes and other bacteria on the surface of the skin that are
    associated with the development of acne. It may also inhibit follicular
    keratinization, which prevents development of acne lesions. The FDA approved
    azelaic acid in September 1995.
  • References: FDA prescribing information

What brand names are available for azelaic acid gel?

Finacea, Azelex

Is azelaic acid gel available as a generic drug?

No

Do I need a prescription for azelaic acid gel?

Yes

What are the uses for azelaic acid gel?

Azelaic acid is used for the treatment of acne vulgaris and treatment
of inflammatory papule and pustules caused by mild to moderate rosacea.

What are the side effects of azelaic acid gel?

  • Common side effects include:
  • Burning
  • Stinging
  • Tingling

Other side effects include:

Other less common side effects include:

What is the dosage for azelaic acid gel?

A thin layer of azelaic acid should be applied and massaged into the affected
areas of the face every 12 hours.

Which drugs or supplements interact with azelaic acid gel?

There are no drug interactions listed for this azelaic
acid.

Is azelaic acid gel safe to take if I’m pregnant or breastfeeding?

  • The safety azelaic acid has not been evaluated. It is not
    known whether azelaic acid is excreted in human milk. However, laboratory
    experiments suggest that the small amount of azelaic acid that is absorbed into
    the body may be excreted in human milk at very low concentrations that may not
    be significant.

What else should I know about azelaic acid gel?

What preparations of azelaic acid gel are available?

Gel, Foam, Kit: 15%. Cream: 20%

How should I keep azelaic acid gel stored?

Store azelaic acid between 15 C and 30 C (59 F and 86 F).

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