Protopic ointment vs. hydrocortisone: What’s the difference? Protopic ointment (acrolimus) and hydrocortisone are topical drugs (for the skin) used to treat atopic dermatitis (eczema). Hydrocortisone is also used for the relief of itching and inflammation caused by a wide variety of skin conditions (for example, insect bites and allergic reactions). Protopic Ointment and hydrocortisone belong …
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Nitrates vs. phosphates: What’s the difference? Nitrates are vasodilators used to treat or prevent heart pain (angina, chest pain) caused by heart disease, usually of the arteries in the heart. Phosphates are laxatives used to clean out the intestines before a colonoscopy. Examples of nitrates include nitroglycerin sublingual tablet (Nitrostat), nitroglycerin lingual aerosol (Nitromist), nitroglycerin pumpspray (Nitrolingual Pumpspray), nitroglycerin transdermal …
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What is sodium iodide I 131, and how does it work (mechanism of action)? Sodium iodide I 131 is an oral medication used to treat hyperthyroidism (overactive thyroid gland) and some cases of thyroid cancer. It falls under the category of an anti-thyroid drug but differs from the other anti-thyroid drugs, propylthiouracil (PTU) and methimazole (Tapazole), because it is radioactive. …
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What is fentanyl, and how does it work (mechanism of action)? Fentanyl is a strong, synthetic (man-made) narcotic that is similar to morphine. A 0.1 mg dose of fentanyl is approximately equal to 10 mg of morphine administered by intramuscular injection. Fentanyl stimulates receptors on nerves in the brain to increase the threshold to pain (the amount of stimulation it …
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What is bisoprolol and hydrochlorothiazide, and how does it work (mechanism of action)? Ziac is a combination product containing bisoprolol (Zebeta) and hydrochlorothiazide (HCTZ). Bisoprolol is a beta-adrenergic receptor blocking agent used for treating high blood pressure and heart pain (angina). Bisoprolol prevents the neurotransmitters (chemicals that nerves use to communicate with other nerves), norepinephrine and epinephrine (adrenaline), from binding …
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What is hyoscyamine, atropine, scopolamine, phenobarbital, and how does it work (mechanism of action)? Belladonna/phenobarbital is an oral medication which combines naturally occurring belladonna alkaloids (atropine, scopolamine [Transderm-Scop], and hyoscyamine) with phenobarbital. It is used for treating abdominal discomfort that is thought to be due to muscular spasm of the intestinal muscles. Belladonna alkaloids block the action of acetylcholine, a …
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What is alosetron, and how does it work (mechanism of action)? Alosetron is used to treat diarrhea and abdominal discomfort that occurs in some women with irritable bowel syndrome (IBS). It works in a similar fashion as granisetron (Kytril), ondansetron (Zofran) and dolasetron (Anzemet) that are used for preventing nausea and vomiting. The discomfort and diarrhea of IBS is believed …
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What is zaleplon, and how does it work (mechanism of action)? Zaleplon is a hypnotic (a medication that induces sleep) that is used for treating insomnia. It is chemically unrelated to the benzodiazepine class of medications for sleep, for example, lorazepam (Ativan), oxazepam (Serax), flurazepam (Dalmane), triazolam (Halcion), and temazepam (Restoril), but it has similar effects because it attaches to …
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What is fluvastatin, and how does it work (mechanism of action)? Fluvastatin is an oral, cholesterol-lowering drug. It belongs to a class of drugs called HMG-CoA reductase inhibitors, commonly called "statins." Other statins include lovastatin (Mevacor), atorvastatin (Lipitor), simvastatin (Zocor), and rosuvastatin (Crestor). Statins reduce cholesterol by inhibiting an enzyme in the liver (HMG-CoA reductase) that is necessary for the …
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What is etidronate, and how does it work (mechanism of action)? Etidronate is in a class of drugs called bisphosphonates that is used for treating osteoporosis (reduced density of bone that leads to fractures) and bone pain from diseases such as metastatic breast cancer, multiple myeloma, and Paget's disease. The bisphosphonate class includes alendronate (Fosamax), ibandronate (Boniva), pamidronate (Aredia), risedronate …
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