What is rituximab? How does it work (mechanism of action)? Rituximab is an intravenous drug that is used to treat rheumatoid arthritis and B-cell non-Hodgkin's lymphoma. It belongs to a class of drugs called monoclonal antibodies. Other monoclonal antibodies include trastuzumab (Herceptin) and gemtuzumab ozogamicin (Mylotarg). Tumor cells (like most normal cells) have receptors on …

What is cyclophosphamide? How does it work (mechanism of action)? Cyclophosphamide is a drug that is used primarily for treating several types of cancer. In order to work, cyclophosphamide first is converted by the liver into two chemicals, acrolein and phosphoramide. Acrolein and phosphoramide are the active compounds, and they slow the growth of cancer cells by interfering with the …

Mesothelioma facts Mesothelioma is a cancer that arises from the cells lining the chest or abdominal cavities. Mesothelioma typically results from exposure to asbestos. When mesothelioma affects the chest, the doctor may look inside the chest cavity with a special instrument called a thoracoscope. When mesothelioma affects the abdomen, the doctor may look inside the abdomen with a special tool …

Taste disorders facts* Readers Comments 35 Share Your Story *Taste disorder facts by John P. Cunha, DO, FACOEP The most common taste disorder is phantom taste perception, which is a lingering, often unpleasant taste even though you have nothing in your mouth. Another type of taste disorder is hypogeusia, a reduced ability to taste sweet, sour, bitter, salty, and savory …

What is metformin? How does it work (mechanism of action)? Metformin is an oral medication that lowers blood glucose (sugar) by influencing the body's sensitivity to insulin and is used for treating type 2 diabetes. Insulin is a hormone produced by the pancreas that controls glucose levels in blood by reducing the amount of glucose made by the liver and …

What is magnesium citrate? How does it work (mechanism of action)? Magnesium citrate is supplied as an oral tablet or liquid saline laxative. Magnesium citrate retains water in the intestines by osmosis. Increasing water in the bowel aids motility, usually producing a bowel movement within one-half to six hours. What are the uses for magnesium citrate? Magnesium citrate is used …

What is losartan, and how does it work (mechanism of action)? Losartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockers (ARBs). Other ARBs include irbesartan (Avapro), valsartan (Diovan), and candesartan (Atacand). Angiotensin formed in the blood by the action of angiotensin converting enzyme (ACE) is a powerful chemical that attaches to angiotensin receptors …

What is Lipitor (atorvastatin)? How does it work (mechanism of action)? Lipitor (atorvastatin) is type of statin that lowers the level of cholesterol in the blood. All statins, including atorvastatin, prevent the production of cholesterol in the liver by blocking HMG-CoA reductase, an enzyme that makes cholesterol. Statins reduce total cholesterol as well as LDL cholesterol in blood. LDL cholesterol …

Multiple sclerosis (MS) and pregnancy definitions and facts Share Your Story Multiple sclerosis (MS) is an autoimmune condition that results in a disruption of information signals between the body and the brain that can cause neurological symptoms. MS is more prevalent in women of childbearing age than in any other group. Symptoms of multiple sclerosis include: Pain Bladder and bowel …

Tommy John surgery (ulnar collateral ligament reconstruction) facts Share Your Story The ulnar collateral ligament (UCL) is the major stabilizer of the elbow. UCL injury is an overuse injury, most often caused by the repetitive motion of throwing. Symptoms include pain over the medial part of the elbow that worsens with throwing and gets better with rest. Usually, health care …