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Lotrel (amlodipine/benazepril) Uses, Side Effects & Dosage

What are the uses for amlodipine and benazepril?

Lotrel is used for treating high blood pressure
(hypertension) when blood pressure is not adequately controlled with either of
its constituent drugs alone.

What brand names are available for amlodipine and benazepril?

Lotrel

Is amlodipine and benazepril available as a generic drug?

Yes

Do I need a prescription for amlodipine and benazepril?

Yes

What are the side effects of amlodipine and benazepril?

Lotrel causes the same side effects as benazepril and amlodipine.

Common side of Lotrel include

Other side effects of Lotrel include




QUESTION

Salt and sodium are the same.
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What is the dosage for amlodipine and benazepril?

The dose of Lotrel is tailored to the patient's needs. The
dose is one capsule once daily.

Which drugs or supplements interact with amlodipine and benazepril?

  • Combining benazepril with potassium
    supplements,
    potassium containing salt substitutes, and potassium conserving diuretics such
    as amiloride (Moduretic),
    spironolactone (Aldactone), and
    triamterene (Dyazide,
    Maxzide), can lead to dangerously high blood levels of potassium.
  • There have
    been reports of increased
    lithium (Eskalith,
    Lithobid) levels when lithium is
    used in combination with
    ACE inhibitors. The reason for this interaction is not
    known, but the increased levels may lead to toxicity from lithium.
  • There have
    been reports that
    aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)
    such as
    ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin,
    Nuprin,
    PediaCare
    Fever, etc.),
    indomethacin (Indocin,
    Indocin-SR), and
    naproxen (Anaprox,
    Naprelan,
    Naprosyn,
    Aleve) may reduce the effects of ACE inhibitors. Combining
    ACE inhibitors with NSAIDs in patients who are elderly, volume-depleted
    (including those on diuretic therapy), or with poor kidney function may result
    in reduced kidney function, including
    kidney failure. These effects usually are
    reversible.
  • Nitritoid reactions (symptoms include facial flushing,
    nausea,
    vomiting and
    low blood pressure or
    hypotension) may occur when injectable gold
    (sodium aurothiomalate), used in the treatment of
    rheumatoid arthritis, is
    combined with ACE inhibitors.
  • Amlodipine increases blood levels of
    simvastatin (Zocor).
    The dose of simvastatin should be limited to 20 mg daily when combined with
    amlodipine.

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Is amlodipine and benazepril safe to take if I’m pregnant or breastfeeding?

  1. ACE inhibitors, including benazepril, can be harmful to the
    fetus and should not be taken by pregnant women.
  2. Small amounts of benazepril are excreted in
    breast
    milk. It is not known whether amlodipine is excreted in breast milk. Lotrel or
    nursing should be discontinued.

What else should I know about amlodipine and benazepril?

What preparations of amlodipine and benazepril are available?

Capsules (mg amlodipine/mg benazepril): 2.5/10;
5/10;5/20; 5/40; 10/20; and 10/40

How should I keep amlodipine and benazepril stored?

Lotrel should be stored at room temperature, 15 C – 30 C (59 C – 86 F).

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