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alemtuzumab (Campath): Leukemia Drug Side Effects & Dosage

What is alemtuzumab, and how does it work (mechanism of action)?

  • Alemtuzumab is an injectable drug used for the treatment of B-cell chronic
    lymphocytic leukemia (B-CLL). People with CLL have too many of a type of white
    blood cell called lymphocytes in the blood and bone marrow. Alemtuzumab is an
    antibody that targets a protein called CD52 that is found on the surface of the
    lymphocytes. Alemtuzumab attaches to lymphocytes and then activates the immune
    system to help kill the lymphocytes.
  • The FDA approved alemtuzumab in May, 2001.

Is alemtuzumab available as a generic drug?

No

Do I need a prescription for alemtuzumab?

Yes

What are the uses for alemtuzumab?

Alemtuzumab is used alone for the treatment of B-cell
chronic
lymphocytic leukemia (B-CLL)

What are the side effects of alemtuzumab?

Common side effects include:

Other side effects include:

What is the dosage for alemtuzumab?

Which drugs or supplements interact with alemtuzumab?

Alemtuzumab drug interaction studies have not been
conducted.

Is alemtuzumab safe to take if I’m pregnant or breastfeeding?

  • Proteins such as alemtuzumab, may cross the placental barrier and may be
    excreted in breast milk. Alemtuzumab has not been studied in
    pregnant women or
    nursing mothers. It should be given to a pregnant or nursing woman only if
    clearly needed.

What else should I know about alemtuzumab?

What preparations of alemtuzumab are available?

Injection (single use vial): 30 mg/vial

How should I keep alemtuzumab stored?

Alemtuzumab should be stored at 2 C to 8 C (36 F to 46 F), protected
from light, and not frozen. If frozen, thaw to 2 to 8 C before administration.

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