What is oral vancomycin? What are the uses for oral vancomycin? Oral vancomycin is a glycopeptide antibiotic that is used for the treatment of Clostridium difficile diarrhea and staphylococcal enterocolitis. Vancomycin is a bactericidal antibiotic (it kills bacteria) that exerts its effects by preventing bacteria from forming cell walls, which they need to survive. Vancomycin …
Read More »
What is misoprostol? What are the uses for misoprostol? Misoprostol is a synthetic (man-made) prostaglandin that is used to reduce the risk of stomach ulcers in patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs, for example, aspirin, ibuprofen, etc.) that are used for pain and various inflammatory conditions, for example, arthritis. Misoprostol is used primarily in patients at high risk for …
Read More »
What is cimetidine, and how does it work (mechanism of action)? Cimetidine is a drug that blocks the production of acid by acid-producing cells in the stomach and can be administered orally, IM or IV. It belongs to a class of drugs called H2 (histamine-2) blockers that also includes ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid). Histamine is a naturally-occurring …
Read More »
What is metoclopramide, and how does it work? Metoclopramide is a "prokinetic" drug that stimulates the muscles of the gastrointestinal tract including the muscles of the lower esophageal sphincter, stomach, and small intestine by interacting with receptors for acetylcholine and dopamine on gastrointestinal muscles and nerves. The lower esophageal sphincter, located between the esophagus and the stomach, normally prevents reflux …
Read More »
What is ursodiol? What are the uses for ursodiol? Ursodiol is a naturally-occurring bile acid that is made by the liver in humans and is secreted in small quantities into bile. It is used to dissolve and prevent cholesterol gallstones and to treat primary biliary cirrhosis, a disease of the liver. Ursodiol blocks the enzyme in the liver that produces …
Read More »
What is linaclotide (Linzess)? What is linaclotide used for? Linaclotide is an oral medication for the treatment of constipation. It is the first in a new class of drugs called guanylate cyclase-C agonists. It is used for relieving symptoms of irritable bowel syndrome (IBS) with constipation and for treating chronic constipation of unknown cause (idiopathic constipation). Linaclotide works locally in …
Read More »
What is bisacodyl? What is bisacodyl used for? Bisacodyl is a stimulant laxative. It stimulates the muscles in the wall of the small intestine and colon to generate a bowel movement. It also alters water and electrolyte levels in intestines, increasing the level of fluids which also produce a laxative-like effect. Bisacodyl is used for for temporary relief of occasional …
Read More »
What is docusate-oral, and how does it work (mechanism of action)? Docusate is a commonly used non-prescription (OTC or over-the-counter) stool softener used to treat or prevent constipation. Docusate is an anionic surfactant that helps lower the surface tension at the oil-water interface of the stool, and thus allows water and lipids or fats to enter the stool. Consequently, fecal …
Read More »
What is simethicone, and how does it work (mechanism of action)? Simethicone is an anti-gas (anti-flatulence) medication. It acts in the stomach and intestines to change the surface tension of gas bubbles, enabling their breakdown and the formation of larger bubbles. In this way it is believed that gas can be eliminated more easily by belching or passing flatus. Simethicone …
Read More »
Carafate vs. omeprazole: What’s the difference? Carafate (sucralfate) and omeprazole are used to treat ulcers and gastroesophageal reflux disease (GERD). Omeprazole is also used to treat Zollinger-Ellison syndrome, duodenitis, erosive esophagitis, heartburn, and H. pylori infection. Brand names for omeprazole include OmePPi, Zegerid, Prilosec, Zegerid, Prilosec OTC, and Zegerid OTC. Some versions of omeprazole are available over-the-counter (OTC). Carafate and …
Read More »