What is lorcaserin (Belviq)? What is it used for? Lorcaserin is an orally administered medication that promotes weight loss. It is used with diet and exercise in overweight adults with a weight-related medical problem or obese adults to lose weight and keep it off. Lorcaserin is a serotonin 2C (5-HT2C) receptor agonist. Although the exact …
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What is cangrelor, and how does it work (mechanism of action)? Cangrelor is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Cangrelor prevents blood clots by reversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. It belongs to a class …
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What is abacavir, and how does it work (mechanism of action)? Abacavir is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), lamivudine (Epivir), emtricitabine (Emtriva), and stavudine (Zerit). During infection with …
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What is auranofin, and how does it work (mechanism of action)? Auranofin is an oral, gold-containing chemical (salt) used for treating rheumatoid arthritis. Other gold salts available are injectable and include aurothioglucose (Solganal) and gold sodium thiomalate (Myochrysine). It is not well understood exactly how gold salts work. In patients with inflammatory arthritis, such as adult and juvenile rheumatoid arthritis, …
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What is aldesleukin, and how does it work (mechanism of action)? Aldesleukin is a man-made protein that has the same action as native human interleukin-2 (IL-2) that is used for treating cancer of the kidney and skin. Interleukins are the messengers by which white blood cells communicate with each other to coordinate inflammation and immunity. Among its actions, IL-2 increases …
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What is lenalidomide (Revlimid)? What is lenalidomide used for? Lenalidomide (Revlimid) is an oral anti-cancer medication. Lenalidomide is similar to thalidomide (Thalomid), an older cancer medicine that, although effective, was associated with serious side effects. The exact mechanism through which lenalidomide stops the growth of cancer cells is not understood. Lenalidomide stimulates or regulates the body’s immune system to attack …
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What is nizatidine, and how does it work (mechanism of action)? Nizatidine is an oral drug that blocks the action of histamine on stomach cells and reduces their production of acid. It belongs to a class of drugs called H2 blockers that also includes cimetidine (Tagamet), ranitidine (Zantac), and famotidine (Pepcid). Histamine is a naturally-occurring chemical that stimulates stomach cells …
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What is desloratadine, and how does it work (mechanism of action)? Desloratadine is an oral, long-acting antihistamine that is similar chemically to loratadine (Claritin). It is used to treat the symptoms caused by histamine. Histamine is a chemical that is responsible for many of the signs and symptoms of allergic reactions, for example, swelling of the lining of the nose, …
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What is sargramostim, and how does it work (mechanism of action)? Sargramostim is a man-made form of the naturally-occurring protein, granulocyte, macrophage-colony stimulating factor (GM-CSF). GM-CSF is produced in the body by the immune system and stimulates the formation of white blood cells, including the granulocyte and the macrophage. Granulocytes and macrophages take part in the inflammatory reaction. They are …
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What is docetaxel, and how does it work (mechanism of action)? Docetaxel is a drug that is used primarily for treating breast cancer. Docetaxel works by attacking cancer cells. Every cell in the body contains a supporting structure (almost like a skeleton) called the microtubular network. If this "skeleton" is changed or damaged, the cell can't grow or reproduce. Docetaxel …
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