What is pentosan, and how does it work (mechanism of action)? Pentosan is a semi-synthetic (man-made) drug that resembles the anticoagulant ("blood thinner") heparin and is used for treating the symptoms of interstitial cystitis. Interstitial cystitis is a condition, usually of unknown cause, in which there is inflammation of the urinary bladder that most frequently …
Read More »ribavirin ( Rebetol, Copegus): Drug Side Effects and Dosage
What is ribavirin, and how does it work (mechanism of action)? Ribavirin is an antiviral drug. It is used in combination with interferon for the treatment of chronic hepatitis C. Although the exact mechanism of its action is unknown, it is thought to interfere with the production and/or action of viral DNA and RNA which are critical to the survival …
Read More »probenecid (Benemid brand no longer available) Side Effects, Dosage
What is probenecid, and how does it work (mechanism of action)? Probenecid is an oral drug used for reducing blood uric acid levels in patients with hyperuricemia (high uric acid) and/or. High uric acid can cause attacks of gout and kidney stones. Probenecid prevents attacks of gout by reducing uric acid levels in the blood. It does this by preventing …
Read More »Protopic Ointment (Acrolimus) vs. Topical Hydrocortisone
Protopic ointment vs. hydrocortisone: What’s the difference? Protopic ointment (acrolimus) and hydrocortisone are topical drugs (for the skin) used to treat atopic dermatitis (eczema). Hydrocortisone is also used for the relief of itching and inflammation caused by a wide variety of skin conditions (for example, insect bites and allergic reactions). Protopic Ointment and hydrocortisone belong to different drug classes. Protopic …
Read More »Nitrates vs. Phosphates: Heart Medication & Laxative Uses & Dosage
Nitrates vs. phosphates: What’s the difference? Nitrates are vasodilators used to treat or prevent heart pain (angina, chest pain) caused by heart disease, usually of the arteries in the heart. Phosphates are laxatives used to clean out the intestines before a colonoscopy. Examples of nitrates include nitroglycerin sublingual tablet (Nitrostat), nitroglycerin lingual aerosol (Nitromist), nitroglycerin pumpspray (Nitrolingual Pumpspray), nitroglycerin transdermal …
Read More »sodium iodide I 131, Iodotope, Sodium Iodide I 131 Therapeutic: Drug Facts, Side Effects and Dosing
What is sodium iodide I 131, and how does it work (mechanism of action)? Sodium iodide I 131 is an oral medication used to treat hyperthyroidism (overactive thyroid gland) and some cases of thyroid cancer. It falls under the category of an anti-thyroid drug but differs from the other anti-thyroid drugs, propylthiouracil (PTU) and methimazole (Tapazole), because it is radioactive. …
Read More »Fentanyl (Sublimaze): Opioid Uses, Side Effects & Dosage
What is fentanyl, and how does it work (mechanism of action)? Fentanyl is a strong, synthetic (man-made) narcotic that is similar to morphine. A 0.1 mg dose of fentanyl is approximately equal to 10 mg of morphine administered by intramuscular injection. Fentanyl stimulates receptors on nerves in the brain to increase the threshold to pain (the amount of stimulation it …
Read More »bisoprolol and hydrochlorothiazide (Ziac): Side Effects & Dosage
What is bisoprolol and hydrochlorothiazide, and how does it work (mechanism of action)? Ziac is a combination product containing bisoprolol (Zebeta) and hydrochlorothiazide (HCTZ). Bisoprolol is a beta-adrenergic receptor blocking agent used for treating high blood pressure and heart pain (angina). Bisoprolol prevents the neurotransmitters (chemicals that nerves use to communicate with other nerves), norepinephrine and epinephrine (adrenaline), from binding …
Read More »hyoscyamine, atropine, scopolamine & phenobarbital Dosage, Side Effects
What is hyoscyamine, atropine, scopolamine, phenobarbital, and how does it work (mechanism of action)? Belladonna/phenobarbital is an oral medication which combines naturally occurring belladonna alkaloids (atropine, scopolamine [Transderm-Scop], and hyoscyamine) with phenobarbital. It is used for treating abdominal discomfort that is thought to be due to muscular spasm of the intestinal muscles. Belladonna alkaloids block the action of acetylcholine, a …
Read More »Lotronex (Generic: Alosetron) IBS Drug Side Effects and Dosage
What is alosetron, and how does it work (mechanism of action)? Alosetron is used to treat diarrhea and abdominal discomfort that occurs in some women with irritable bowel syndrome (IBS). It works in a similar fashion as granisetron (Kytril), ondansetron (Zofran) and dolasetron (Anzemet) that are used for preventing nausea and vomiting. The discomfort and diarrhea of IBS is believed …
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