What is clindamycin and benzoyl peroxide gel, and how does it work (mechanism of action)? Clindamycin/benzoyl peroxide is a combination of an antibiotic, clindamycin, and benzoyl peroxide, another drug that has antibacterial effects. Clindamycin/benzoyl peroxide is used topically (applied to the skin) for the treatment of pimples (acne). Both agents are active against Propionibacterium acnes, …
Read More »
What is tincture of opium liquid, and how does it work (mechanism of action)? Opium tincture is an oral liquid medication used to control diarrhea. Opium tincture contains morphine which is an opioid pain reliever. Opioids can reduce gastrointestinal motility, propulsion, secretions, and increase gastrointestinal muscle tone. These effects help in controlling diarrhea. Opium tincture is a controlled substance. What …
Read More »
What is trimipramine, and how does it work (mechanism of action)? Trimipramine is a tricyclic antidepressant (TCA) in the same family as amitriptyline (Elavil), imipramine (Tofranil), nortriptyline (Pamelor; Aventyl), and desipramine (Norpramin). Trimipramine works by raising the brain's level of norepinephrine (a neurotransmitter) to more normal levels. It also has anti-cholinergic actions (opposing the effects of the neurotransmitter, acetylcholine) which …
Read More »
What is mifepristone, and how does it work (mechanism of action)? Mifepristone is a synthetic steroid with antiprogesterone and antiglucocorticoid effects. It is used for terminating pregnancy and treating people with Cushing syndrome. Progesterone is a female hormone and the principal progestational hormone. Progesterone prepares the uterus (the womb) to receive and sustain the fertilized egg andis an important hormone …
Read More »
What is leuprolide, and how does it work (mechanism of action)? Leuprolide is an injectable, man-made hormone that is used for treating prostate cancer, endometriosis, central precocious puberty (early onset of puberty), and fibroids. It is similar to but stronger than human gonadotropin releasing hormone (GnRH). GnRH is made in the hypothalamus (a part of the brain) and travels to …
Read More »
What is letrozole, and how does it work (mechanism of action)? Letrozole is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the …
Read More »
What is dextrose solution-intravenous, and how does it work (mechanism of action)? Dextrose monohydrate is sterile intravenous solution for fluid replenishment. Intravenous administration of dextrose solution provides a source of water and glucose ( sugar), giving patients fluid and energy. What brand names are available for dextrose solution-intravenous? N/A Is dextrose solution-intravenous available as a generic drug? Yes Do I …
Read More »
What is ezetimibe and simvastatin, and how does it work (mechanism of action)? Vytorin is a combination of ezetimibe (Zetia) and simvastatin (Zocor) that is used for treating high levels of cholesterol in the blood. Vytorin reduces total cholesterol and low density lipoprotein (LDL or "bad") cholesterol while it increases high density lipoprotein (HDL or "good") cholesterol. The ezetimibe component …
Read More »
What is pimecrolimus, and how does it work (mechanism of action)? Pimecrolimus is a chemical that is used to treat atopic dermatitis (eczema). Atopic dermatitis is a skin condition characterized by redness, itching, scaling, and inflammation of the skin. The cause of atopic dermatitis is not known; however, scientists believe that it may be due to activation of the immune …
Read More »
What is glycopyrrolate, and how does it work (mechanism of action)? Glycopyrrolate is a synthetic anti-cholinergic medication. Glycopyrrolate works by blocking acetylcholine activity on smooth muscles and other tissues. Acetylcholine is neurotransmitter, a chemical that nerves use for communicating. Blocking of acetylcholine leads to decrease in volume and acidity of stomach secretions and decrease in pharyngeal, tracheal, and bronchial secretions. …
Read More »