What is Pravachol, and how does it work? Pravachol is a prescription medicine used to treat the symptoms of high cholesterol, to lower blood levels of “bad” cholesterol (low-density lipoprotein or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL) and to lower triglycerides. Pravachol may be used alone or with other medications. …
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What is Zypitamag and how does it work? Zypitamag (pitavastatin) tablets are an HMG-CoA reductase inhibitor indicated for patients with primary hyperlipidemia or mixed dyslipidemia as an adjunctive therapy to diet to reduce elevated total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG), and to increase high-density lipoprotein cholesterol (HDL-C). Zypitamag (pitavastatin) is an inhibitor of …
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What is FloLipid and how does it work? FloLipid Oral Suspension is a lipid-lowering agent that is derived synthetically from a fermentation product of Aspergillus terreus. After oral ingestion, simvastatin, which is an inactive lactone, is hydrolyzed to the corresponding β-hydroxyacid form. This is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, …
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What is Liptruzet and how does it work? Liptruzet is indicated for the reduction of elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG), and non-high-density lipoprotein cholesterol (non-HDL-C), and to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia or mixed hyperlipidemia. Liptruzet contains ezetimibe, a selective inhibitor of …
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What are the common causes of high cholesterol? Factors that may increase bad cholesterol in the body Below are few common factors that may increase bad cholesterol in the body: Hereditary: Cholesterol or heart diseases may run in the family and is usually inherited. Comorbid diseases: Diabetes, liver diseases, and kidney and thyroid diseases Smoking cigarettes or passive smoking: Cigarette …
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What is Repatha, and what is it used for? Repatha (evolocumab) Injection, an antibody cholesterol medication, is a human monoclonal immunoglobulin G2 (IgG2) as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (CVD), who require additional lowering of low density lipoprotein cholesterol (LDL-C). Repatha is also indicated as an adjunct to diet and other LDL-lowering therapies (e.g., statins, ezetimibe, LDL apheresis) …
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What are statins, and how do they work? “Statins” is a class of drugs that lowers the level of cholesterol in the blood by reducing the production of cholesterol by the liver. (The other source of cholesterol in the blood is dietary cholesterol.) Statins block the enzyme in the liver that is responsible for making cholesterol. This enzyme is called …
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Rhabdomyolysis facts What Is Rhabdomyolysis? Rhabdomyolysis is the rapid destruction of skeletal muscle resulting in leakage into the urine of the muscle protein myoglobin. Rhabdomyolysis has many causes. Medications can cause muscle injury and rhabdomyolysis. Rhabdomyolysis can cause muscle pain and weakness. Blood levels of muscle enzymes, including CPK, SGOT, SGPT, and LDH, as well as blood and urine myoglobin …
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Triglyceride test definition and facts Readers Comments 6 Share Your Story Diagram showing makeup of HDL and LDL cholesterol types measured by triglyceride tests Elevated triglyceride levels may be a risk factor for atherosclerosis. Highly elevated triglyceride levels may also cause fatty liver disease and pancreatitis. High triglyceride levels can also be associated with diabetes, kidney disease, and the use …
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What is alirocumab, and how does it work (mechanism of action)? Alirocumab is a man-made injectable drug that reduces cholesterol levels in the blood. It is the first member of a new class of drugs called proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors. Cholesterol is carried in the blood to a large extent by particles of low density lipoproteins …
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