What is indinavir, and how does it work (mechanism of action)? Indinavir is an oral medication that is used for treating infections with the human immunodeficiency virus (HIV). It is in a class of drugs called protease inhibitors which also includes ritonavir (Norvir), nelfinavir (Viracept) and saquinavir (Invirase, Fortovase). During infection with HIV, the HIV …
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What is fingolimod? What is fingolimod used for? Fingolimod is an oral medication used for treating multiple sclerosis (MS). Its mechanism of action is unknown, although it may work by reducing the number of circulating lymphocytes (a type of white blood cell), leading to reduced migration of white blood cells into the central nervous system. White blood cells cause inflammation …
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What is secukinumab? What is secukinumab used for? Secukinumab is an injectable biologic drug that suppresses the immune system and is used for the treatment of psoriasis. It is an antibody that binds to interleukin 17A (IL-17A), a chemical produced by cells in the body that stimulates immune reactions. Scientists believe that psoriasis is caused by an increase in the …
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What is auranofin, and how does it work (mechanism of action)? Auranofin is an oral, gold-containing chemical (salt) used for treating rheumatoid arthritis. Other gold salts available are injectable and include aurothioglucose (Solganal) and gold sodium thiomalate (Myochrysine). It is not well understood exactly how gold salts work. In patients with inflammatory arthritis, such as adult and juvenile rheumatoid arthritis, …
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What is aldesleukin, and how does it work (mechanism of action)? Aldesleukin is a man-made protein that has the same action as native human interleukin-2 (IL-2) that is used for treating cancer of the kidney and skin. Interleukins are the messengers by which white blood cells communicate with each other to coordinate inflammation and immunity. Among its actions, IL-2 increases …
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What is atazanavir, and how does it work (mechanism of action)? Atazanavir is an oral medication that is used for treating infections caused by the human immunodeficiency virus (HIV). It is in a class of drugs called protease inhibitors that also includes ritonavir (Norvir), nelfinavir (Viracept), indinavir (Crixivan) and saquinavir (Invirase, Fortovase). During infection with HIV, the HIV virus multiplies …
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Throat cancer (larynx cancer) facts* Readers Comments 33 Share Your Story HPV infection, cigarette smoking, alcoholism, and asbestos exposure are risk factors for throat cancer. *Throat cancer (larynx cancer) facts author: Melissa Conrad Stöppler, MD The larynx is the voice box located at the top of the windpipe (trachea). Cancer of the larynx occurs most often in people over the …
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What is lenalidomide (Revlimid)? What is lenalidomide used for? Lenalidomide (Revlimid) is an oral anti-cancer medication. Lenalidomide is similar to thalidomide (Thalomid), an older cancer medicine that, although effective, was associated with serious side effects. The exact mechanism through which lenalidomide stops the growth of cancer cells is not understood. Lenalidomide stimulates or regulates the body’s immune system to attack …
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What is nizatidine, and how does it work (mechanism of action)? Nizatidine is an oral drug that blocks the action of histamine on stomach cells and reduces their production of acid. It belongs to a class of drugs called H2 blockers that also includes cimetidine (Tagamet), ranitidine (Zantac), and famotidine (Pepcid). Histamine is a naturally-occurring chemical that stimulates stomach cells …
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What is desloratadine, and how does it work (mechanism of action)? Desloratadine is an oral, long-acting antihistamine that is similar chemically to loratadine (Claritin). It is used to treat the symptoms caused by histamine. Histamine is a chemical that is responsible for many of the signs and symptoms of allergic reactions, for example, swelling of the lining of the nose, …
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