What is hydrocortisone-rectal cream, ointment, and how does it work (mechanism of action)? Hydrocortisone is a natural corticosteroid produced by the adrenal glands that are located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties and are used in a wide variety of inflammatory conditions such as: arthritis, colitis, asthma, bronchitis, certain skin rashes, and …

Atomoxetine vs. Adderall comparison Atomoxetine (Strattera) and Adderall (amphetamine and dextroamphetamine) are both used to treat attention deficit hyperactivity disorder ADHD (Adderall can also treat narcolepsy). Atomoxetine, however, is the first ADHD drug that is non-addictive, whereas Adderall and other ADHD drugs (like Ritalin) are stimulants with a high potential for abuse. Although it is not known precisely how atomoxetine …

Sudden infant death syndrome (SIDS) facts Sudden infant death syndrome is the sudden, unexpected death of an infant younger than 1 year of age. It typically occurs associated with a period of sleep. SIDS is rare during the first month of life. Risk peaks in infants 2-4 months of age and then declines. Medical professionals diagnose SIDS once all recognizable …

What is phenylephrine-injection, and how does it work (mechanism of action)? Phenylephrine is a man-made drug that stimulates receptors (alpha1 receptors) on blood vessels and cause blood vessels to constrict (vasoconstriction). It is a vasoconstrictor medication, structurally similar to epinephrine and ephedrine. Vasoconstriction increases blood pressure. Phenylephrine increases blood pressure and heart rate without affecting heart rhythm. What brand names …

What is methotrexate, and how does it work (mechanism of action)? Methotrexate is classified as an antimetabolite drug which means it is capable of blocking the metabolism of cells. (Metabolism consists of the production and destruction of important components of the cell as well as the production of energy for use by the cell.) As a result of this effect, …

Lexapro vs. Effexor Lexapro (escitalopram) and Effexor (venlafaxine) are antidepressants used for treatment of major depression. Lexapro is also used to treat anxiety in adults. The brand name Effexor has been discontinued in the U.S. It is available in generic form. Lexapro belongs to the drug class selective serotonin reuptake inhibitors (SSRIs) while Effexor is a selective serotonin and norepinephrine …

What is St. John’s wort (Hypericum perforatum)-oral, and how does it work (mechanism of action)? St. John's wort is a commonly used over-the-counter (OTC) dietary supplement that is used to treat mild depression, anxiety, and sleep disorders. St. John's wort is a plant that has bright yellow flowers. A number of compounds that have pharmacological activity including naphthodianthrones (hypericin, pseudohypericin, …

What is fluticasone propionate oral inhaler, and how does it work (mechanism of action)? Fluticasone propionate is a man-made steroid of the glucocorticoid family which is related to the naturally-occurring steroid hormone, cortisol or hydrocortisone, produced by the adrenal glands. Glucocorticoid steroids have potent anti-inflammatory actions. When used as an inhaler, fluticasone travels to the airways in the lung. In …

What is eszopiclone, and how does it work (mechanism of action)? Eszopiclone is a non-benzodiazepine, oral, sedative drug ("sleeping pill") that is used for treating insomnia. According to the National Institutes of Health, more than 50 million Americans suffer from insomnia. Symptoms of insomnia include difficulty falling asleep, awakening frequently during the night, waking up too early, an inability to …

What is estrogens conjugated, and how does it work (mechanism of action)? Estrogens are one of the two major classes of female hormones. (Progestins comprise the second major class). Estrogens are used primarily to treat the symptoms of menopause and states in which there is a deficiency of estrogen, for example, in women who have had their ovaries removed. Conjugated …