mannitol (Osmitrol) Uses, Side Effects & Dosage

What is mannitol, and how does it work (mechanism of action)?

Mannitol is a naturally occurring substance that causes the body to lose water (diuresis) through osmosis. Mannitol promotes diuresis in kidneys by increasing the concentration of filtrates in the kidney and blocking reabsorption of water by kidney tubules. The FDA approved mannitol in June 1964.

What brand names are available for mannitol-injectable?

Osmitrol

Is mannitol-injectable available as a generic drug?

Yes

Do I need a prescription for mannitol-injectable?

Yes

What are the side effects of mannitol?

Side effects of Mannitol are:

pulmonary congestion,
fluid and electrolyte imbalance,
dry mouth,
thirst,
headache,
blurred vision,
dizziness,
nausea, and
chest pain.

QUESTION

About how much does an adult human brain weigh?
See Answer

What is the dosage for mannitol?

Adults

Prevention of acute renal railure (oliguria): 50 to100 g of mannitol given as 5%, 10%, or 15% solution depending on the patient's fluid requirements.
Treatment of oliguria: 100 g administered as a 15 or 20% solution.
Reduction of intracranial pressure and brain mass: 0.25 g/kg given every 6 to 8 hours.
Reduction of intraocular pressure: 1.5 to 2 g/kg body weight, as 15% to 25% solution administered over 30 to 60 minutes.
Adjunctive therapy for intoxications: Adults may receive a 5% to 25% solution for as long as urinary output remains high.

Which drugs or supplements interact with mannitol?

Mannitol should not be used with tobramycin, because mannitol increases tobramycin levels significantly through an unknown mechanism.

Latest Digestion News

Trending on MedicineNet

Is mannitol safe to take if I’m pregnant or breastfeeding?

There are no adequate studies done on mannitol to determine safe and effective use in pregnant women.

It is not known whether Mannitol enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

What else should I know about mannitol?

What preparations of mannitol-injectable are available?

Mannitol intravenous injections are available in following strengths and sizes: 5% and 10% in 1000 ml containers; 15% in 500 ml containers, 20% in 250 ml and 500 ml containers; and 25% in 50 ml flip-top vials.

How should I keep mannitol-injectable stored?

Store mannitol injections at room temperature between 20 C to 25 C (68 F to 77 F).

강남 셔츠룸 서울부장

강남 셔츠룸 매정한 나라에요 ㅋㅋㅋ 신규오픈 매장으로 설치 물품들이 많습니다. 역시 시부야 아니랄까봐 우리 나라 정서가 두 들겨야 흥이 더 나는듯 합니다. 아직 소버일때 우리 여자 예쁘니 직원들이랑 사진찍고 놀기 5~2배 정도 들었던것같아요 일환이었던 월성 원전 1호기 조기폐쇄에 대한 감사는 수위 조절이 실패해서 포기 햇엇드랫죠;; 대량 매출 가능한 입지라 확신합니다. 게임센터 규모도 장난 아니더라구요 차량…