Coenzyme Q10 (ubiquinone): Benefits and Side Effects

What is coenzyme Q10 (ubiquinone, ubidecarenone)-oral, and how does it work (mechanism of action)?

Coenzyme Q10 or CoQ10 is naturally produced in the
body and is present in the heart, kidney, pancreas, and liver.
It is a fat soluble antioxidant and an important chemical used in oxidative respiration for
the Krebs cycle and the electron transport chain both of which are critical for
the generation of energy that is used by all cells in the body.
Coenzyme Q10 levels decrease with age and may be low in people with heart diseases,
Parkinson’s, disease, cancers, muscular dystrophies, and diabetes.

What brand names are available for coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

Acanda COQ10 Soft Gels, Doctor’s Best High Absorption Coq10,
Omegaboost Coq-10, Kirkland Signature CoQ10, and many others

Is coenzyme Q10 (ubiquinone, ubidecarenone)-oral available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

What are the uses for coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

Coenzyme Q10 may be effective for treating coenzyme Q10 deficiency.
It is possibly effective for improving vision in people with age-related macular
degeneration (AMD or ARMD); improving heart function in people with congestive
heart failure; improving symptoms of diabetic neuropathy; improving immune
function in people with HIV; reducing blood pressure; reducing the
frequency of migraine attacks; and improving physical performance in people with
muscular dystrophy.
Coenzyme Q10 produced in the laboratory is a component of
many herbal products and has many uses.

QUESTION

According to the USDA, there is no difference between a “portion” and a “serving.”
See Answer

What are the side effects of coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

The common side effects of coenzyme Q10 are:

Stomach upset
Decreased appetite
Diarrhea
Increased levels of liver enzymes in the blood
Nausea

Other side effects of coenzyme Q10 include:

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What is the dosage for coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

Doses vary depending on the use. The typical dose for treating
coenzyme Q10 deficiency is 150 mg daily.
High blood pressure is treated with 120
to 200 mg daily in two divided doses.
The dose for preventing migraine headaches
is 100 mg three times daily.
Doses of 300 to 2400 mg per day have been used for
treating Parkinson’s disease.

Which drugs or supplements interact with coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

Taking coenzyme Q10 with medications, herbs, or
supplements that reduce blood pressure may cause too much reduction in blood
pressure.

Coenzyme Q10 may help blood to clot. Therefore, it may reduce the
blood thinning effect of warfarin (Coumadin).

Is coenzyme Q10 (ubiquinone, ubidecarenone)-oral safe to take if I’m pregnant or breastfeeding?

Coenzyme Q10 has been used safely by pregnant women starting at 20 weeks
gestation until term.

It is not known if coenzyme Q10 is excreted in breast milk.

What else should I know about coenzyme Q10 (ubiquinone, ubidecarenone)-oral?

What preparations of coenzyme Q10 (ubiquinone, ubidecarenone)-oral are available?

Soft Gel Tablets: 100 and 300 mg; Capsule: 30, 50, 200,
and 400 mg; Gummies: 100 mg

How should I keep coenzyme Q10 (ubiquinone, ubidecarenone)-oral stored?

Coenzyme Q10 should be stored at room temperature 20 C to 25 C (68 F
to 77 F).